Hipersensibilidad a metales en pacientes con implantes ortopédicos.

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Title: Hipersensibilidad a metales en pacientes con implantes ortopédicos.
Authors: Sánchez Olivas, Manuel Anastacio1, Valencia Zavala, Martha Patricia1 alergia_1617@hotmail.com, Sánchez Olivas, Jesús Alberto2, Velázquez, Guadalupe Sepúlveda3
Source: Revista Alergia de Mexico. jul/ago2010, Vol. 57 Issue 4, p127-130. 4p.
Subjects: ALLERGIES, ORTHOPEDIC implants, ELECTROCHEMISTRY, METAL ions, CORROSION & anti-corrosives, HAPTENS, IMMUNE response
Abstract (English): All metals in contact with biological systems suffer corrosion, which is an electrochemical process that causes metallic ions formation, known as haptens, which link with endogenous or exogenous proteins, therefore inducing an immune response. A hypersensitivity response to an implanted material should be suspected when cutaneous lesions or inflammatory reactions occur proximal to or surrounding the site of the metallic orthopedic implant. At present there is no a reliable diagnostic test for the determination of hypersensitivity to implanted metallic devices. It has been shown that the products of corrosive degradation are associated with dermatitis, urticaria and vasculitis. Cutaneous lesions in patients with unsuccessful metallic implants are more frequent than in non-rejected implants or the general population. Although the cellular and humoral hypersensitivity response in metallic orthopedic implants has been clearly identified, the risk is very low. Nowadays the importance of hypersensitivity to metals as a contributing factor in the failure of implants is unknown. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Todos los metales en contacto con sistemas biológicos experimentan corrosión. De este proceso electroquímico se forman iones metálicos, conocidos como haptenos, los cuales, al unirse a proteínas endógenas o exógenas, pueden inducir una respuesta inmunitaria. Debe sospecharse una respuesta de hipersensibilidad al material implantado cuando aparecen lesiones cutáneas o reacciones inflamatorias próximas al sitio donde se ha colocado un implante ortopédico metálico. Actualmente se carece de una prueba diagnóstica confiable para determinar la hipersensibilidad a los metales de los dispositivos implantados. Se ha demostrado que los productos de la degradación corrosiva de los implantes se asocian con dermatitis, urticaria y vasculitis. Son más frecuentes las lesiones cutáneas en pacientes con implantes metálicos fallidos que en implantes sin rechazo o en la población en general. Aunque se ha identificado claramente la respuesta de hipersensibilidad celular y humoral a los implantes ortopédicos metálicos, el riesgo parece mínimo. Actualmente se desconoce la importancia de la hipersensibilidad a los metales como un factor contribuyente a la falla de los implantes. [ABSTRACT FROM AUTHOR]
Copyright of Revista Alergia de Mexico is the property of Coleg. Mexicano de Inmunologia Clinica y Alergia A.C.; Soc. Lat. de Alergia, Asma e Inmunologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Hipersensibilidad a metales en pacientes con implantes ortopédicos.
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  Data: <searchLink fieldCode="AR" term="%22Sánchez+Olivas%2C+Manuel+Anastacio%22">Sánchez Olivas, Manuel Anastacio</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Valencia+Zavala%2C+Martha+Patricia%22">Valencia Zavala, Martha Patricia</searchLink><relatesTo>1</relatesTo><i> alergia_1617@hotmail.com</i><br /><searchLink fieldCode="AR" term="%22Sánchez+Olivas%2C+Jesús+Alberto%22">Sánchez Olivas, Jesús Alberto</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Velázquez%2C+Guadalupe+Sepúlveda%22">Velázquez, Guadalupe Sepúlveda</searchLink><relatesTo>3</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Revista+Alergia+de+Mexico%22">Revista Alergia de Mexico</searchLink>. jul/ago2010, Vol. 57 Issue 4, p127-130. 4p.
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  Data: <searchLink fieldCode="DE" term="%22ALLERGIES%22">ALLERGIES</searchLink><br /><searchLink fieldCode="DE" term="%22ORTHOPEDIC+implants%22">ORTHOPEDIC implants</searchLink><br /><searchLink fieldCode="DE" term="%22ELECTROCHEMISTRY%22">ELECTROCHEMISTRY</searchLink><br /><searchLink fieldCode="DE" term="%22METAL+ions%22">METAL ions</searchLink><br /><searchLink fieldCode="DE" term="%22CORROSION+%26+anti-corrosives%22">CORROSION & anti-corrosives</searchLink><br /><searchLink fieldCode="DE" term="%22HAPTENS%22">HAPTENS</searchLink><br /><searchLink fieldCode="DE" term="%22IMMUNE+response%22">IMMUNE response</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: All metals in contact with biological systems suffer corrosion, which is an electrochemical process that causes metallic ions formation, known as haptens, which link with endogenous or exogenous proteins, therefore inducing an immune response. A hypersensitivity response to an implanted material should be suspected when cutaneous lesions or inflammatory reactions occur proximal to or surrounding the site of the metallic orthopedic implant. At present there is no a reliable diagnostic test for the determination of hypersensitivity to implanted metallic devices. It has been shown that the products of corrosive degradation are associated with dermatitis, urticaria and vasculitis. Cutaneous lesions in patients with unsuccessful metallic implants are more frequent than in non-rejected implants or the general population. Although the cellular and humoral hypersensitivity response in metallic orthopedic implants has been clearly identified, the risk is very low. Nowadays the importance of hypersensitivity to metals as a contributing factor in the failure of implants is unknown. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Todos los metales en contacto con sistemas biológicos experimentan corrosión. De este proceso electroquímico se forman iones metálicos, conocidos como haptenos, los cuales, al unirse a proteínas endógenas o exógenas, pueden inducir una respuesta inmunitaria. Debe sospecharse una respuesta de hipersensibilidad al material implantado cuando aparecen lesiones cutáneas o reacciones inflamatorias próximas al sitio donde se ha colocado un implante ortopédico metálico. Actualmente se carece de una prueba diagnóstica confiable para determinar la hipersensibilidad a los metales de los dispositivos implantados. Se ha demostrado que los productos de la degradación corrosiva de los implantes se asocian con dermatitis, urticaria y vasculitis. Son más frecuentes las lesiones cutáneas en pacientes con implantes metálicos fallidos que en implantes sin rechazo o en la población en general. Aunque se ha identificado claramente la respuesta de hipersensibilidad celular y humoral a los implantes ortopédicos metálicos, el riesgo parece mínimo. Actualmente se desconoce la importancia de la hipersensibilidad a los metales como un factor contribuyente a la falla de los implantes. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Revista Alergia de Mexico is the property of Coleg. Mexicano de Inmunologia Clinica y Alergia A.C.; Soc. Lat. de Alergia, Asma e Inmunologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Text: Spanish
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        PageCount: 4
        StartPage: 127
    Subjects:
      – SubjectFull: ALLERGIES
        Type: general
      – SubjectFull: ORTHOPEDIC implants
        Type: general
      – SubjectFull: ELECTROCHEMISTRY
        Type: general
      – SubjectFull: METAL ions
        Type: general
      – SubjectFull: CORROSION & anti-corrosives
        Type: general
      – SubjectFull: HAPTENS
        Type: general
      – SubjectFull: IMMUNE response
        Type: general
    Titles:
      – TitleFull: Hipersensibilidad a metales en pacientes con implantes ortopédicos.
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            NameFull: Sánchez Olivas, Manuel Anastacio
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            NameFull: Valencia Zavala, Martha Patricia
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            NameFull: Sánchez Olivas, Jesús Alberto
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              Text: jul/ago2010
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              Y: 2010
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