Prescripción y vigilancia de la inmunoterapia sublingual con vacunas estandarizadas de ácaros domésticos en un servicio de alergología.
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| Title: | Prescripción y vigilancia de la inmunoterapia sublingual con vacunas estandarizadas de ácaros domésticos en un servicio de alergología. |
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| Alternate Title: | Prescription and surveillance of the sublingual immunotherapy with standardized domestic mite vaccines in allergology service. |
| Authors: | Álvarez, Mirta1 mirtaac@infomed.sld.cu, Castro, Raúl Lázaro2, Gutiérrez, Daniel Ramón1, Labrada, Alexis2, Enríquez, Irene1, Ronquillo, Mercedes1, Rodríguez, José1 |
| Source: | Revista VacciMonitor (Vacunología y Temas Afines). sep-dic2012, Vol. 21 Issue 3, p13-18. 6p. |
| Subjects: | IMMUNOTHERAPY, ALLERGENS, VACCINES, DRUG tolerance, SUBLINGUAL gland, MITES, VACCINATION complications |
| Abstract (English): | Allergen-specific immunotherapy consists of administering gradually increasing doses of the allergen, to which the patient is sensitized, aiming at achieving tolerance to it and decreasing clinical symptoms. The sublingual immunotherapy (SLIT) was introduced as an alternative to subcutaneous route. The objective was to assess the safety of sublingual standardized vaccines of three domestic mite species (VALERGEN, Cuba) and its adverse events in allergic patients from the Calixto García University Hospital in Havana, as well as the frequency of the vaccine prescription. A descriptive and cross sectional study design included 130 patients with treatment of SLIT with VALERGEN (BIOCEN, Cuba), who attended the Allergy Service in the period from January to September 2010. Age distribution: mean 19.6 years (range 1-75), 40.7% was younger than 18 years. The multiallergen vaccine was the most used (63.8%). The most common allergen was D. pteronyssinus followed by B. tropicalis. 71.55% of administered allergens vaccines were in maintenance phase. We found 4 adverse events (3.1% of patients), all local, mild, and not requiring treatment or change of dosing schedule. The VALERGEN vaccines by sublingual route were shown to be safe and well tolerated in Cuban allergic patients. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Las vacunas terapéuticas para la alergia, también llamadas inmunoterapia alergeno específica, consisten en la administración de dosis progresivamente crecientes del alergeno al cual el individuo está sensibilizado, con el objetivo de alcanzar tolerancia al mismo y disminuir la sintomatología clínica. Se realizó un estudio descriptivo, de corte transversal para determinar la seguridad de las vacunas de ácaros domésticos (VALERGEN), administradas mediante gotas por vía sublingual. Se verificaron sus eventos adversos en pacientes alérgicos, atendidos en el Departamento de Alergología del hospital universitario "Calixto García", que asistieron a cambios de vacunas en el mes de septiembre de 2010, así como la frecuencia de prescripción de vacunas alergénicas en el período enero-septiembre del mismo año. Se incluyeron 130 pacientes con tratamiento de inmunoterapia sublingual con VALERGEN, con una edad media de 19,6 años (rango 1-75); el 40,7% tenía 17 años o menos. El tipo de vacuna más empleada resultó ser la multialergénica (63,8%). El ácaro más empleado fue el Dermatophagoides pteronyssinus, seguido de Blomia tropicalis. El 71,55% de los casos se encontraban en fase de mantenimiento. Se reportaron cuatro eventos adversos (3,1%) locales leves, que no requirieron tratamiento ni cambio de pauta de vacunación. Se comprobó que las vacunas sublinguales VALERGEN son seguras y bien toleradas en los pacientes alérgicos. [ABSTRACT FROM AUTHOR] |
| Copyright of Revista VacciMonitor (Vacunología y Temas Afines) is the property of Vacunas Finlay S.A. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: lth DbLabel: MedicLatina An: 82746221 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Prescripción y vigilancia de la inmunoterapia sublingual con vacunas estandarizadas de ácaros domésticos en un servicio de alergología. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: Prescription and surveillance of the sublingual immunotherapy with standardized domestic mite vaccines in allergology service. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Álvarez%2C+Mirta%22">Álvarez, Mirta</searchLink><relatesTo>1</relatesTo><i> mirtaac@infomed.sld.cu</i><br /><searchLink fieldCode="AR" term="%22Castro%2C+Raúl+Lázaro%22">Castro, Raúl Lázaro</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Gutiérrez%2C+Daniel+Ramón%22">Gutiérrez, Daniel Ramón</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Labrada%2C+Alexis%22">Labrada, Alexis</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Enríquez%2C+Irene%22">Enríquez, Irene</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ronquillo%2C+Mercedes%22">Ronquillo, Mercedes</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Rodríguez%2C+José%22">Rodríguez, José</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Revista+VacciMonitor+%28Vacunología+y+Temas+Afines%29%22">Revista VacciMonitor (Vacunología y Temas Afines)</searchLink>. sep-dic2012, Vol. 21 Issue 3, p13-18. 6p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22IMMUNOTHERAPY%22">IMMUNOTHERAPY</searchLink><br /><searchLink fieldCode="DE" term="%22ALLERGENS%22">ALLERGENS</searchLink><br /><searchLink fieldCode="DE" term="%22VACCINES%22">VACCINES</searchLink><br /><searchLink fieldCode="DE" term="%22DRUG+tolerance%22">DRUG tolerance</searchLink><br /><searchLink fieldCode="DE" term="%22SUBLINGUAL+gland%22">SUBLINGUAL gland</searchLink><br /><searchLink fieldCode="DE" term="%22MITES%22">MITES</searchLink><br /><searchLink fieldCode="DE" term="%22VACCINATION+complications%22">VACCINATION complications</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: Allergen-specific immunotherapy consists of administering gradually increasing doses of the allergen, to which the patient is sensitized, aiming at achieving tolerance to it and decreasing clinical symptoms. The sublingual immunotherapy (SLIT) was introduced as an alternative to subcutaneous route. The objective was to assess the safety of sublingual standardized vaccines of three domestic mite species (VALERGEN, Cuba) and its adverse events in allergic patients from the Calixto García University Hospital in Havana, as well as the frequency of the vaccine prescription. A descriptive and cross sectional study design included 130 patients with treatment of SLIT with VALERGEN (BIOCEN, Cuba), who attended the Allergy Service in the period from January to September 2010. Age distribution: mean 19.6 years (range 1-75), 40.7% was younger than 18 years. The multiallergen vaccine was the most used (63.8%). The most common allergen was D. pteronyssinus followed by B. tropicalis. 71.55% of administered allergens vaccines were in maintenance phase. We found 4 adverse events (3.1% of patients), all local, mild, and not requiring treatment or change of dosing schedule. The VALERGEN vaccines by sublingual route were shown to be safe and well tolerated in Cuban allergic patients. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Las vacunas terapéuticas para la alergia, también llamadas inmunoterapia alergeno específica, consisten en la administración de dosis progresivamente crecientes del alergeno al cual el individuo está sensibilizado, con el objetivo de alcanzar tolerancia al mismo y disminuir la sintomatología clínica. Se realizó un estudio descriptivo, de corte transversal para determinar la seguridad de las vacunas de ácaros domésticos (VALERGEN), administradas mediante gotas por vía sublingual. Se verificaron sus eventos adversos en pacientes alérgicos, atendidos en el Departamento de Alergología del hospital universitario "Calixto García", que asistieron a cambios de vacunas en el mes de septiembre de 2010, así como la frecuencia de prescripción de vacunas alergénicas en el período enero-septiembre del mismo año. Se incluyeron 130 pacientes con tratamiento de inmunoterapia sublingual con VALERGEN, con una edad media de 19,6 años (rango 1-75); el 40,7% tenía 17 años o menos. El tipo de vacuna más empleada resultó ser la multialergénica (63,8%). El ácaro más empleado fue el Dermatophagoides pteronyssinus, seguido de Blomia tropicalis. El 71,55% de los casos se encontraban en fase de mantenimiento. Se reportaron cuatro eventos adversos (3,1%) locales leves, que no requirieron tratamiento ni cambio de pauta de vacunación. Se comprobó que las vacunas sublinguales VALERGEN son seguras y bien toleradas en los pacientes alérgicos. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Revista VacciMonitor (Vacunología y Temas Afines) is the property of Vacunas Finlay S.A. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=lth&AN=82746221 |
| RecordInfo | BibRecord: BibEntity: Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 6 StartPage: 13 Subjects: – SubjectFull: IMMUNOTHERAPY Type: general – SubjectFull: ALLERGENS Type: general – SubjectFull: VACCINES Type: general – SubjectFull: DRUG tolerance Type: general – SubjectFull: SUBLINGUAL gland Type: general – SubjectFull: MITES Type: general – SubjectFull: VACCINATION complications Type: general Titles: – TitleFull: Prescripción y vigilancia de la inmunoterapia sublingual con vacunas estandarizadas de ácaros domésticos en un servicio de alergología. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Álvarez, Mirta – PersonEntity: Name: NameFull: Castro, Raúl Lázaro – PersonEntity: Name: NameFull: Gutiérrez, Daniel Ramón – PersonEntity: Name: NameFull: Labrada, Alexis – PersonEntity: Name: NameFull: Enríquez, Irene – PersonEntity: Name: NameFull: Ronquillo, Mercedes – PersonEntity: Name: NameFull: Rodríguez, José IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: sep-dic2012 Type: published Y: 2012 Identifiers: – Type: issn-print Value: 1025028X Numbering: – Type: volume Value: 21 – Type: issue Value: 3 Titles: – TitleFull: Revista VacciMonitor (Vacunología y Temas Afines) Type: main |
| ResultId | 1 |
