Anuario 2012: La terapia celular en la enfermedad cardiovascular. Las revistas de las Sociedades Nacionales presentan una selección de las investigaciones que han impulsado avances recientes en Cardiología Clínica.
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| Title: | Anuario 2012: La terapia celular en la enfermedad cardiovascular. Las revistas de las Sociedades Nacionales presentan una selección de las investigaciones que han impulsado avances recientes en Cardiología Clínica. |
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| Alternate Title: | Almanac 2012: Cell therapy in cardiovascular disease. The National Society Journals present selected research that has driven recent advances in Clinical Cardiology. |
| Authors: | Jones, Daniel A.1,2,3, Choudry, Fizzah1,3, Mathur, y. Anthony1,2,3 a.mathur@qmul.ac.uk |
| Source: | CorSalud. 2013, Vol. 5 Issue 1, p43-54. 12p. |
| Subjects: | CARDIOVASCULAR disease treatment, CELLULAR therapy, CARDIOLOGY, GENETIC translation, REGENERATIVE medicine, CLINICAL trials, HEART diseases, THERAPEUTICS, TREATMENT effectiveness |
| Abstract (English): | The rapid translation from bench to bedside that has been seen in the application of regenerative medicine to cardiology has led to exciting new advances in our understanding of some of the fundamental mecha-nisms related to human biology. The first generation of cells used in phase I-II trials (mainly bone marrow mononuclear cells) are now entering phase III clinical trials with the goal of producing a cell based therapeutic that can change the outcome of cardiac disease. First generation cell therapy appears to have addressed safety concerns as well as showing 'activity' in numerous published meta-analyses. With the know-ledge gained to date, the field is moving towards the next generation of cells-the 'engineered' cell-that have been developed to display a phenotype that will fur-ther enhance the myocardial repair/salvage process. This almanac review covers the latest basic research that may soon have application to humans as well as the results of the latest clinical trials. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | La rápida puesta en práctica de la investigación de transferencia que se ha visto en la aplicación de la me-dicina regenerativa a la cardiología ha dado lugar a interesantes avances en nuestra comprensión de algunos de los mecanismos fundamentales relacionados con la biología humana. La primera generación de células utilizadas en ensayos fase I-II (principalmente células mononucleares de la médula ósea), están en-trando ahora en la fase III de los ensayos clínicos, con el objetivo de producir una estrategia terapéutica basada en células que puedan cambiar el pronóstico de la enfermedad cardíaca. La primera generación de terapia celular parece haber abordado las preocupa-ciones de seguridad, y mostró "actividad" en numero-sos meta-análisis publicados. Con los conocimientos adquiridos hasta el momento, esta disciplina se está moviendo hacia la próxima generación de células -las células modificadas-, que se han desarrollado para mostrar un fenotipo que mejorará aún más el proceso de reparación/rescate del miocardio. Este anuario cubre las últimas investigaciones básicas que pueden tener aplicación en los seres humanos próximamente, así como los resultados de los últimos ensayos clínicos. [ABSTRACT FROM AUTHOR] |
| Copyright of CorSalud is the property of Cardiocentro Ernesto Che Guevara and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | MedicLatina |
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| Header | DbId: lth DbLabel: MedicLatina An: 84771477 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Anuario 2012: La terapia celular en la enfermedad cardiovascular. Las revistas de las Sociedades Nacionales presentan una selección de las investigaciones que han impulsado avances recientes en Cardiología Clínica. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: Almanac 2012: Cell therapy in cardiovascular disease. The National Society Journals present selected research that has driven recent advances in Clinical Cardiology. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Jones%2C+Daniel+A%2E%22">Jones, Daniel A.</searchLink><relatesTo>1,2,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Choudry%2C+Fizzah%22">Choudry, Fizzah</searchLink><relatesTo>1,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Mathur%2C+y%2E+Anthony%22">Mathur, y. Anthony</searchLink><relatesTo>1,2,3</relatesTo><i> a.mathur@qmul.ac.uk</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22CorSalud%22">CorSalud</searchLink>. 2013, Vol. 5 Issue 1, p43-54. 12p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22CARDIOVASCULAR+disease+treatment%22">CARDIOVASCULAR disease treatment</searchLink><br /><searchLink fieldCode="DE" term="%22CELLULAR+therapy%22">CELLULAR therapy</searchLink><br /><searchLink fieldCode="DE" term="%22CARDIOLOGY%22">CARDIOLOGY</searchLink><br /><searchLink fieldCode="DE" term="%22GENETIC+translation%22">GENETIC translation</searchLink><br /><searchLink fieldCode="DE" term="%22REGENERATIVE+medicine%22">REGENERATIVE medicine</searchLink><br /><searchLink fieldCode="DE" term="%22CLINICAL+trials%22">CLINICAL trials</searchLink><br /><searchLink fieldCode="DE" term="%22HEART+diseases%22">HEART diseases</searchLink><br /><searchLink fieldCode="DE" term="%22THERAPEUTICS%22">THERAPEUTICS</searchLink><br /><searchLink fieldCode="DE" term="%22TREATMENT+effectiveness%22">TREATMENT effectiveness</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: The rapid translation from bench to bedside that has been seen in the application of regenerative medicine to cardiology has led to exciting new advances in our understanding of some of the fundamental mecha-nisms related to human biology. The first generation of cells used in phase I-II trials (mainly bone marrow mononuclear cells) are now entering phase III clinical trials with the goal of producing a cell based therapeutic that can change the outcome of cardiac disease. First generation cell therapy appears to have addressed safety concerns as well as showing 'activity' in numerous published meta-analyses. With the know-ledge gained to date, the field is moving towards the next generation of cells-the 'engineered' cell-that have been developed to display a phenotype that will fur-ther enhance the myocardial repair/salvage process. This almanac review covers the latest basic research that may soon have application to humans as well as the results of the latest clinical trials. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: La rápida puesta en práctica de la investigación de transferencia que se ha visto en la aplicación de la me-dicina regenerativa a la cardiología ha dado lugar a interesantes avances en nuestra comprensión de algunos de los mecanismos fundamentales relacionados con la biología humana. La primera generación de células utilizadas en ensayos fase I-II (principalmente células mononucleares de la médula ósea), están en-trando ahora en la fase III de los ensayos clínicos, con el objetivo de producir una estrategia terapéutica basada en células que puedan cambiar el pronóstico de la enfermedad cardíaca. La primera generación de terapia celular parece haber abordado las preocupa-ciones de seguridad, y mostró "actividad" en numero-sos meta-análisis publicados. Con los conocimientos adquiridos hasta el momento, esta disciplina se está moviendo hacia la próxima generación de células -las células modificadas-, que se han desarrollado para mostrar un fenotipo que mejorará aún más el proceso de reparación/rescate del miocardio. Este anuario cubre las últimas investigaciones básicas que pueden tener aplicación en los seres humanos próximamente, así como los resultados de los últimos ensayos clínicos. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of CorSalud is the property of Cardiocentro Ernesto Che Guevara and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1136/heartjnl-2011-301540 Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 12 StartPage: 43 Subjects: – SubjectFull: CARDIOVASCULAR disease treatment Type: general – SubjectFull: CELLULAR therapy Type: general – SubjectFull: CARDIOLOGY Type: general – SubjectFull: GENETIC translation Type: general – SubjectFull: REGENERATIVE medicine Type: general – SubjectFull: CLINICAL trials Type: general – SubjectFull: HEART diseases Type: general – SubjectFull: THERAPEUTICS Type: general – SubjectFull: TREATMENT effectiveness Type: general Titles: – TitleFull: Anuario 2012: La terapia celular en la enfermedad cardiovascular. Las revistas de las Sociedades Nacionales presentan una selección de las investigaciones que han impulsado avances recientes en Cardiología Clínica. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Jones, Daniel A. – PersonEntity: Name: NameFull: Choudry, Fizzah – PersonEntity: Name: NameFull: Mathur, y. Anthony IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: 2013 Type: published Y: 2013 Identifiers: – Type: issn-print Value: 20787170 Numbering: – Type: volume Value: 5 – Type: issue Value: 1 Titles: – TitleFull: CorSalud Type: main |
| ResultId | 1 |
