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NIVELES DE PLOMO EN GESTANTES Y NEONATOS EN LA CIUDAD DE LA OROYA, PERÚ.

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Title: NIVELES DE PLOMO EN GESTANTES Y NEONATOS EN LA CIUDAD DE LA OROYA, PERÚ.
Alternate Title: LEAD LEVELS IN PREGNANT WOMEN AND NEWBORNS IN LA OROYA CITY, PERU.
Authors: Castro-Bedriñana, Jorge1 jorgecastrobe@yahoo.com, Chirinos-Peinado, Doris1, Ríos-Ríos, Elva2
Source: Revista Peruana de Medicina Experimental y Salud Pública. jul-sep2013, Vol. 30 Issue 3, p393-398. 6p.
Subjects: PREGNANT women, NEWBORN infants, BLOOD products, CROSS-sectional method, BLOOD sampling, ATOMIC absorption spectroscopy
Geographic Terms: PERU
Abstract (English): Objectives. To determine blood-lead (Pb) levels in pregnant women and neonates in a metallurgical city of Peru. Materials and methods. Across-sectional study was carried out, the population of which consisted of pregnant women who had lived for at least two years in the city of La Oroya, at the time when the lead, copper and zinc foundries operated normally. A blood sample was obtained from the pregnant women before delivery and, after delivery, from the neonate's umbilical cord and placenta. Lead levels in those samples were measured by graphite furnace atomic absorption spectrophotometry. Pearson's squared regressions and correlations were determined. Results. Forty normal deliveries were studied. The average blood lead levels in the mother, umbilical cord and placenta were 27.4 ± 15.6 ug/dL; 19.0 ± 12.6 ug/dL and 319.0 ± 215.9 ug/100 g, respectively. 67.5% of the neonates registered levels higher than 10 ug/dL. Pb levels in the umbilical cord accounted for 69.4% of Pb level in maternal blood. The correlation coefficients between Pb levels in maternal blood and umbilical cord, maternal blood and placenta, and placenta and umbilical cord were 0.36; 0.48 and 0.33, respectively. Conclusions. At the time the foundry operated, pregnant women and newborns had high blood lead concentrations. Pb concentrations in the placenta and umbilical cord had moderate correlation with the Pb levels in maternal blood. Pb levels in maternal blood and umbilical cord were 1.5 times as high as in more distant areas. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): Objetivos. Determinar los niveles de plomo (Pb) en gestantes y neonatos en la ciudad de La Oroya, Perú. Materiales y métodos. Se realizó un estudio transversal. La población estuvo conformada por gestantes residentes durante al menos dos años en la ciudad de La Oroya, cuando operaban normalmente las fundiciones de Pb, cobre y zinc. Se obtuvo muestras de sangre de la gestante antes del parto y luego del parto se tomaron muestras de placenta y sangre del cordón umbilical. El nivel de Pb de dichas muestras fue evaluado por espectrometría de absorción atómica con horno de grafito. Se determinaron regresiones cuadráticas y correlaciones de Pearson. Resultados. Se evaluó cuarenta partos normales. Los niveles promedio de Pb en la sangre materna, cordon umbilical y placenta fueron 27,4 ± 15,6 ug/dL; 19,0 ± 12,6 ug/dL y 319,0 ± 215,9 ug/100 g, respectivamente. El 67,5% de los neonatos tuvieron más de 10 ug/dL de Pb. El nivel de Pb de la sangre del cordón umbilical representó el 69,4% del nivel de Pb en sangre materna. Los coeficientes de correlación entre el Pb de la sangre materna y cordón umbilical, sangre materna y placenta, placenta y sangre del cordón umbilical fueron 0,36; 0,48 y 0,33, respectivamente. Conclusiones. Cuando funcionaba la fundición, las gestantes y recién nacidos tenían concentraciones elevadas de Pb en sangre. Las concentraciones de Pb en la placenta y cordón umbilical tuvieron una correlación moderada con el Pb de la sangre materna. El Pb de la sangre materna y cordón umbilical fue 1,5 veces más alto que los de zonas más alejadas. [ABSTRACT FROM AUTHOR]
Copyright of Revista Peruana de Medicina Experimental y Salud Pública is the property of Instituto Nacional de Salud (Peru) and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: MedicLatina
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  Data: NIVELES DE PLOMO EN GESTANTES Y NEONATOS EN LA CIUDAD DE LA OROYA, PERÚ.
– Name: TitleAlt
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  Data: LEAD LEVELS IN PREGNANT WOMEN AND NEWBORNS IN LA OROYA CITY, PERU.
– Name: Author
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  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Castro-Bedriñana%2C+Jorge%22">Castro-Bedriñana, Jorge</searchLink><relatesTo>1</relatesTo><i> jorgecastrobe@yahoo.com</i><br /><searchLink fieldCode="AR" term="%22Chirinos-Peinado%2C+Doris%22">Chirinos-Peinado, Doris</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ríos-Ríos%2C+Elva%22">Ríos-Ríos, Elva</searchLink><relatesTo>2</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Revista+Peruana+de+Medicina+Experimental+y+Salud+Pública%22">Revista Peruana de Medicina Experimental y Salud Pública</searchLink>. jul-sep2013, Vol. 30 Issue 3, p393-398. 6p.
– Name: Subject
  Label: Subjects
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  Data: <searchLink fieldCode="DE" term="%22PREGNANT+women%22">PREGNANT women</searchLink><br /><searchLink fieldCode="DE" term="%22NEWBORN+infants%22">NEWBORN infants</searchLink><br /><searchLink fieldCode="DE" term="%22BLOOD+products%22">BLOOD products</searchLink><br /><searchLink fieldCode="DE" term="%22CROSS-sectional+method%22">CROSS-sectional method</searchLink><br /><searchLink fieldCode="DE" term="%22BLOOD+sampling%22">BLOOD sampling</searchLink><br /><searchLink fieldCode="DE" term="%22ATOMIC+absorption+spectroscopy%22">ATOMIC absorption spectroscopy</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22PERU%22">PERU</searchLink>
– Name: Abstract
  Label: Abstract (English)
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  Data: Objectives. To determine blood-lead (Pb) levels in pregnant women and neonates in a metallurgical city of Peru. Materials and methods. Across-sectional study was carried out, the population of which consisted of pregnant women who had lived for at least two years in the city of La Oroya, at the time when the lead, copper and zinc foundries operated normally. A blood sample was obtained from the pregnant women before delivery and, after delivery, from the neonate's umbilical cord and placenta. Lead levels in those samples were measured by graphite furnace atomic absorption spectrophotometry. Pearson's squared regressions and correlations were determined. Results. Forty normal deliveries were studied. The average blood lead levels in the mother, umbilical cord and placenta were 27.4 ± 15.6 ug/dL; 19.0 ± 12.6 ug/dL and 319.0 ± 215.9 ug/100 g, respectively. 67.5% of the neonates registered levels higher than 10 ug/dL. Pb levels in the umbilical cord accounted for 69.4% of Pb level in maternal blood. The correlation coefficients between Pb levels in maternal blood and umbilical cord, maternal blood and placenta, and placenta and umbilical cord were 0.36; 0.48 and 0.33, respectively. Conclusions. At the time the foundry operated, pregnant women and newborns had high blood lead concentrations. Pb concentrations in the placenta and umbilical cord had moderate correlation with the Pb levels in maternal blood. Pb levels in maternal blood and umbilical cord were 1.5 times as high as in more distant areas. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: Objetivos. Determinar los niveles de plomo (Pb) en gestantes y neonatos en la ciudad de La Oroya, Perú. Materiales y métodos. Se realizó un estudio transversal. La población estuvo conformada por gestantes residentes durante al menos dos años en la ciudad de La Oroya, cuando operaban normalmente las fundiciones de Pb, cobre y zinc. Se obtuvo muestras de sangre de la gestante antes del parto y luego del parto se tomaron muestras de placenta y sangre del cordón umbilical. El nivel de Pb de dichas muestras fue evaluado por espectrometría de absorción atómica con horno de grafito. Se determinaron regresiones cuadráticas y correlaciones de Pearson. Resultados. Se evaluó cuarenta partos normales. Los niveles promedio de Pb en la sangre materna, cordon umbilical y placenta fueron 27,4 ± 15,6 ug/dL; 19,0 ± 12,6 ug/dL y 319,0 ± 215,9 ug/100 g, respectivamente. El 67,5% de los neonatos tuvieron más de 10 ug/dL de Pb. El nivel de Pb de la sangre del cordón umbilical representó el 69,4% del nivel de Pb en sangre materna. Los coeficientes de correlación entre el Pb de la sangre materna y cordón umbilical, sangre materna y placenta, placenta y sangre del cordón umbilical fueron 0,36; 0,48 y 0,33, respectivamente. Conclusiones. Cuando funcionaba la fundición, las gestantes y recién nacidos tenían concentraciones elevadas de Pb en sangre. Las concentraciones de Pb en la placenta y cordón umbilical tuvieron una correlación moderada con el Pb de la sangre materna. El Pb de la sangre materna y cordón umbilical fue 1,5 veces más alto que los de zonas más alejadas. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: <i>Copyright of Revista Peruana de Medicina Experimental y Salud Pública is the property of Instituto Nacional de Salud (Peru) and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Text: Spanish
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        StartPage: 393
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      – SubjectFull: PREGNANT women
        Type: general
      – SubjectFull: NEWBORN infants
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      – SubjectFull: BLOOD products
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      – SubjectFull: CROSS-sectional method
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      – SubjectFull: BLOOD sampling
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      – SubjectFull: ATOMIC absorption spectroscopy
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      – TitleFull: NIVELES DE PLOMO EN GESTANTES Y NEONATOS EN LA CIUDAD DE LA OROYA, PERÚ.
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              Text: jul-sep2013
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