¿Qué adyuvante es mejor en la anestesia regional: sufentanyl o fentanyl en cirugía ortopédica de miembros inferiores?

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Title: ¿Qué adyuvante es mejor en la anestesia regional: sufentanyl o fentanyl en cirugía ortopédica de miembros inferiores?
Authors: Oriol-López, Salomé Alejandra1, Hernández-Bernal, Clara E.1, Rodríguez-Rosales, Asael2
Source: Revista Mexicana de Anestesiología. abr-jun2013, Vol. 36 Issue 2, p85-92. 8p. 4 Charts, 3 Graphs.
Subjects: OPIOIDS, ANESTHESIA research, ANESTHETICS, PHARMACODYNAMICS, EPIDURAL analgesia, LIDOCAINE, BENZODIAZEPINES, CONDUCTION anesthesia
Abstract (English): The use of epidural opioid in regional anesthesia is occasional, which leads to the use of rescue doses of epidural anesthetic and intravenous drugs to sedate the patient. Numerous studies have compared the efficacy of sufentanyl against fentanyl via epidural in obstetric and postoperative analgesia, the first being five times more potent (epidural dose 21 µg); however, there are no significant differences. Methodology: Compare the anesthesia with lidocaine and sufentanyl (20 µg) contrasted with lidocaine + fentanyl (50 µg) in 70 patients for lower limbs surgery (orthopedics), measuring the amount of local anesthetic, opioid, benzodiazepines, atropine, ephedrine, as well as heart rate, systolic blood pressure, diastolic and mean, the Bromage and diffusion level obtained. Results: Hemodynamic stability is similar in both groups, the differences were found in the use of subsequent local anesthetic, number of doses, epidural opioid, benzodiazepines and intravenous opioid, even when sufentanyl's dose is less than the reported as useful in this way. [ABSTRACT FROM AUTHOR]
Abstract (Spanish): En anestesia regional se utiliza poco el opioide por vía epidural, lo que conlleva el empleo de dosis de rescate de anestésico epidural y fármacos endovenosos para sedar al paciente. Numerosos estudios han comparado la efi cacia del sufentanyl contra fentanyl por vía epidural en analgesia obstétrica y postoperatoria, siendo cinco veces más potente el primero (dosis epidural 21 µg); no obstante, no hay diferencias significativas. Metodología: Se comparó la anestesia obtenida con lidocaína + sufentanyl (20 µg) contrastada con lidocaína + fentanyl (50 µg) en 70 pacientes para cirugía de miembros inferiores (ortopedia), midiéndose la cantidad de anestésico, opioide, benzodiacepinas, atropina, efedrina, así como la frecuencia cardíaca, presiones arteriales sistólica, diastólica y media, el Bromage y nivel de difusión obtenido. Resultados: La estabilidad hemodinámica es similar en ambos grupos; las diferencias se encontraron en el uso del anestésico local subsecuente, número de dosis, de opioide epidural, así como de benzodiacepinas y opioide endovenoso, aun cuando la dosis de sufentanyl es menor a la reportada como útil por esta vía. [ABSTRACT FROM AUTHOR]
Copyright of Revista Mexicana de Anestesiología is the property of Colegio Mexicano de Anestesiologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: ¿Qué adyuvante es mejor en la anestesia regional: sufentanyl o fentanyl en cirugía ortopédica de miembros inferiores?
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  Data: <searchLink fieldCode="JN" term="%22Revista+Mexicana+de+Anestesiología%22">Revista Mexicana de Anestesiología</searchLink>. abr-jun2013, Vol. 36 Issue 2, p85-92. 8p. 4 Charts, 3 Graphs.
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  Data: <searchLink fieldCode="DE" term="%22OPIOIDS%22">OPIOIDS</searchLink><br /><searchLink fieldCode="DE" term="%22ANESTHESIA+research%22">ANESTHESIA research</searchLink><br /><searchLink fieldCode="DE" term="%22ANESTHETICS%22">ANESTHETICS</searchLink><br /><searchLink fieldCode="DE" term="%22PHARMACODYNAMICS%22">PHARMACODYNAMICS</searchLink><br /><searchLink fieldCode="DE" term="%22EPIDURAL+analgesia%22">EPIDURAL analgesia</searchLink><br /><searchLink fieldCode="DE" term="%22LIDOCAINE%22">LIDOCAINE</searchLink><br /><searchLink fieldCode="DE" term="%22BENZODIAZEPINES%22">BENZODIAZEPINES</searchLink><br /><searchLink fieldCode="DE" term="%22CONDUCTION+anesthesia%22">CONDUCTION anesthesia</searchLink>
– Name: Abstract
  Label: Abstract (English)
  Group: Ab
  Data: The use of epidural opioid in regional anesthesia is occasional, which leads to the use of rescue doses of epidural anesthetic and intravenous drugs to sedate the patient. Numerous studies have compared the efficacy of sufentanyl against fentanyl via epidural in obstetric and postoperative analgesia, the first being five times more potent (epidural dose 21 µg); however, there are no significant differences. Methodology: Compare the anesthesia with lidocaine and sufentanyl (20 µg) contrasted with lidocaine + fentanyl (50 µg) in 70 patients for lower limbs surgery (orthopedics), measuring the amount of local anesthetic, opioid, benzodiazepines, atropine, ephedrine, as well as heart rate, systolic blood pressure, diastolic and mean, the Bromage and diffusion level obtained. Results: Hemodynamic stability is similar in both groups, the differences were found in the use of subsequent local anesthetic, number of doses, epidural opioid, benzodiazepines and intravenous opioid, even when sufentanyl's dose is less than the reported as useful in this way. [ABSTRACT FROM AUTHOR]
– Name: Abstract
  Label: Abstract (Spanish)
  Group: Ab
  Data: En anestesia regional se utiliza poco el opioide por vía epidural, lo que conlleva el empleo de dosis de rescate de anestésico epidural y fármacos endovenosos para sedar al paciente. Numerosos estudios han comparado la efi cacia del sufentanyl contra fentanyl por vía epidural en analgesia obstétrica y postoperatoria, siendo cinco veces más potente el primero (dosis epidural 21 µg); no obstante, no hay diferencias significativas. Metodología: Se comparó la anestesia obtenida con lidocaína + sufentanyl (20 µg) contrastada con lidocaína + fentanyl (50 µg) en 70 pacientes para cirugía de miembros inferiores (ortopedia), midiéndose la cantidad de anestésico, opioide, benzodiacepinas, atropina, efedrina, así como la frecuencia cardíaca, presiones arteriales sistólica, diastólica y media, el Bromage y nivel de difusión obtenido. Resultados: La estabilidad hemodinámica es similar en ambos grupos; las diferencias se encontraron en el uso del anestésico local subsecuente, número de dosis, de opioide epidural, así como de benzodiacepinas y opioide endovenoso, aun cuando la dosis de sufentanyl es menor a la reportada como útil por esta vía. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Revista Mexicana de Anestesiología is the property of Colegio Mexicano de Anestesiologia and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Text: Spanish
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        PageCount: 8
        StartPage: 85
    Subjects:
      – SubjectFull: OPIOIDS
        Type: general
      – SubjectFull: ANESTHESIA research
        Type: general
      – SubjectFull: ANESTHETICS
        Type: general
      – SubjectFull: PHARMACODYNAMICS
        Type: general
      – SubjectFull: EPIDURAL analgesia
        Type: general
      – SubjectFull: LIDOCAINE
        Type: general
      – SubjectFull: BENZODIAZEPINES
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      – SubjectFull: CONDUCTION anesthesia
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      – TitleFull: ¿Qué adyuvante es mejor en la anestesia regional: sufentanyl o fentanyl en cirugía ortopédica de miembros inferiores?
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            NameFull: Oriol-López, Salomé Alejandra
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            NameFull: Hernández-Bernal, Clara E.
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            NameFull: Rodríguez-Rosales, Asael
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              Text: abr-jun2013
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              Y: 2013
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