Factores de riesgo asociados con episodios de hipoglucemia grave en pacientes diabéticos.
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| Title: | Factores de riesgo asociados con episodios de hipoglucemia grave en pacientes diabéticos. |
|---|---|
| Alternate Title: | Risk Factors Related to Severe Hypoglycemia Episodes in Diabetic Patients. |
| Authors: | Dehesa-López, Edgar1 dredgardehesa@gmail.com, Manzanarez-Moreno, Ismaldo2, Quintero-Pérez, Alberto3 |
| Source: | Medicina Interna de México. jul-ago2014, Vol. 30 Issue 4, p407-418. 12p. 6 Charts. |
| Subjects: | ENDOCRINOLOGY, HYPOGLYCEMIA, PEOPLE with diabetes, CASE-control method, LOGISTIC regression analysis, DISEASES, DISEASE risk factors |
| Abstract (English): | Background: Hypoglycemia is a frequent complication in patients with diabetes mellitus. Furthermore it has a negative impact on morbidity, mortality and quality of life of these patients. Objective: To identify risk factors associated with episodes of severe hypoglycemia in patients with diabetes mellitus. Material and method: A case-control study was performed including 58 patients with diabetes mellitus who were admitted to the emergency department with a diagnosis of severe hypoglycemia and 63 controls diabetic patients. Binary logistic regression was used to study the effect of clinical, demographic and laboratorial characteristics for severe hypoglycemia risk. Results: Mean age was 63 ± 13 years, 66.1% (n = 80) were female and 95% had diabetes mellitus 2. Risk factors associated with severe hypoglycemia were: age with OR of 1.12 (95% CI 1.05-1.20; p = 0.01), administration of secretagogues with OR of 9.92 (95% CI 1.56-63.22; p = 0.02), administration of NPH insulin with OR of 131.99 (95% IC 8.5- 2,049.9; p = 0.01) and number of previous hypoglycemic events with OR 26.33 (95% IC 3.92-176.71; p = 0.01). Protective factors against severe hypoglycemia were: previous follow up by internal medicine doctor with OR of 0.07 (95% CI 0.01-0.35; p = 0.01) and previous follow up by endocrinologist with OR of 0.01 (95% CI 0.00-0.40; p = 0.02). Conclusions: Risk factors for severe hypoglycemia were: age, previous hypoglycemic event, administration of NPH insulin and secretagogues. Interestingly, follow up by specialist doctor had an important role in reducing the risk of severe hypoglycemia. [ABSTRACT FROM AUTHOR] |
| Abstract (Spanish): | Antecedentes: la hipoglucemia es una complicación aguda frecuente en los pacientes con diabetes mellitus y conlleva un efecto negativo en la morbilidad, mortalidad y la calidad de vida de estos pacientes. Objetivos: identificar los factores de riesgo asociados con episodios de hipoglucemia grave en pacientes con diabetes mellitus. Material y método: estudio de casos y controles hospitalarios. Se incluyeron 58 pacientes diabéticos que ingresaron al servicio de urgencias con diagnóstico de hipoglucemia grave y 63 pacientes diabéticos controles. Mediante regresión logística binaria se estudió el efecto de covariables clínicas, demográficas y de laboratorio para la aparición de hipoglucemia grave. Resultados: el promedio de edad de los pacientes fue de 63 ± 13 años, 66.1% (n = 80) era del sexo femenino y 95% tenía diabetes mellitus tipo 2. Los factores de riesgo asociados con hipoglucemia grave fueron: edad con OR de 1.12 (IC 95% 1.05-1.20; p = 0.01), administración de secretagogos con OR de 9.92 (IC 95% 1.56-63.22; p = 0.02), administración de insulina NPH con OR de 131.99 (IC 95% 8.5-2,049.9; p = 0.01) y número de eventos previos de hipoglucemia con OR de 26.33 (IC 95% 3.92-176.71; p = 0.01). Los factores protectores contra hipoglucemia grave fueron: el seguimiento previo por un médico internista con OR de 0.07 (IC 95% 0.01-0.35; p = 0.01) y por un endocrinólogo con OR de 0.01 (IC 95% 0.00-0.40; p = 0.02). Conclusiones: los factores de riesgo de hipoglucemia grave fueron: edad, evento previo de hipoglucemia, administración de insulina NPH y secretagogos. De manera interesante, el nivel de especialización del médico en el tratamiento de los pacientes con diabetes mellitus tuvo un papel importante en la reducción del riesgo de hipoglucemia. [ABSTRACT FROM AUTHOR] |
| Copyright of Medicina Interna de México is the property of Colegio de Medicina Interna de Mexico and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
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| Items | – Name: Title Label: Title Group: Ti Data: Factores de riesgo asociados con episodios de hipoglucemia grave en pacientes diabéticos. – Name: TitleAlt Label: Alternate Title Group: TiAlt Data: Risk Factors Related to Severe Hypoglycemia Episodes in Diabetic Patients. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Dehesa-López%2C+Edgar%22">Dehesa-López, Edgar</searchLink><relatesTo>1</relatesTo><i> dredgardehesa@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Manzanarez-Moreno%2C+Ismaldo%22">Manzanarez-Moreno, Ismaldo</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Quintero-Pérez%2C+Alberto%22">Quintero-Pérez, Alberto</searchLink><relatesTo>3</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Medicina+Interna+de+México%22">Medicina Interna de México</searchLink>. jul-ago2014, Vol. 30 Issue 4, p407-418. 12p. 6 Charts. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22ENDOCRINOLOGY%22">ENDOCRINOLOGY</searchLink><br /><searchLink fieldCode="DE" term="%22HYPOGLYCEMIA%22">HYPOGLYCEMIA</searchLink><br /><searchLink fieldCode="DE" term="%22PEOPLE+with+diabetes%22">PEOPLE with diabetes</searchLink><br /><searchLink fieldCode="DE" term="%22CASE-control+method%22">CASE-control method</searchLink><br /><searchLink fieldCode="DE" term="%22LOGISTIC+regression+analysis%22">LOGISTIC regression analysis</searchLink><br /><searchLink fieldCode="DE" term="%22DISEASES%22">DISEASES</searchLink><br /><searchLink fieldCode="DE" term="%22DISEASE+risk+factors%22">DISEASE risk factors</searchLink> – Name: Abstract Label: Abstract (English) Group: Ab Data: Background: Hypoglycemia is a frequent complication in patients with diabetes mellitus. Furthermore it has a negative impact on morbidity, mortality and quality of life of these patients. Objective: To identify risk factors associated with episodes of severe hypoglycemia in patients with diabetes mellitus. Material and method: A case-control study was performed including 58 patients with diabetes mellitus who were admitted to the emergency department with a diagnosis of severe hypoglycemia and 63 controls diabetic patients. Binary logistic regression was used to study the effect of clinical, demographic and laboratorial characteristics for severe hypoglycemia risk. Results: Mean age was 63 ± 13 years, 66.1% (n = 80) were female and 95% had diabetes mellitus 2. Risk factors associated with severe hypoglycemia were: age with OR of 1.12 (95% CI 1.05-1.20; p = 0.01), administration of secretagogues with OR of 9.92 (95% CI 1.56-63.22; p = 0.02), administration of NPH insulin with OR of 131.99 (95% IC 8.5- 2,049.9; p = 0.01) and number of previous hypoglycemic events with OR 26.33 (95% IC 3.92-176.71; p = 0.01). Protective factors against severe hypoglycemia were: previous follow up by internal medicine doctor with OR of 0.07 (95% CI 0.01-0.35; p = 0.01) and previous follow up by endocrinologist with OR of 0.01 (95% CI 0.00-0.40; p = 0.02). Conclusions: Risk factors for severe hypoglycemia were: age, previous hypoglycemic event, administration of NPH insulin and secretagogues. Interestingly, follow up by specialist doctor had an important role in reducing the risk of severe hypoglycemia. [ABSTRACT FROM AUTHOR] – Name: Abstract Label: Abstract (Spanish) Group: Ab Data: Antecedentes: la hipoglucemia es una complicación aguda frecuente en los pacientes con diabetes mellitus y conlleva un efecto negativo en la morbilidad, mortalidad y la calidad de vida de estos pacientes. Objetivos: identificar los factores de riesgo asociados con episodios de hipoglucemia grave en pacientes con diabetes mellitus. Material y método: estudio de casos y controles hospitalarios. Se incluyeron 58 pacientes diabéticos que ingresaron al servicio de urgencias con diagnóstico de hipoglucemia grave y 63 pacientes diabéticos controles. Mediante regresión logística binaria se estudió el efecto de covariables clínicas, demográficas y de laboratorio para la aparición de hipoglucemia grave. Resultados: el promedio de edad de los pacientes fue de 63 ± 13 años, 66.1% (n = 80) era del sexo femenino y 95% tenía diabetes mellitus tipo 2. Los factores de riesgo asociados con hipoglucemia grave fueron: edad con OR de 1.12 (IC 95% 1.05-1.20; p = 0.01), administración de secretagogos con OR de 9.92 (IC 95% 1.56-63.22; p = 0.02), administración de insulina NPH con OR de 131.99 (IC 95% 8.5-2,049.9; p = 0.01) y número de eventos previos de hipoglucemia con OR de 26.33 (IC 95% 3.92-176.71; p = 0.01). Los factores protectores contra hipoglucemia grave fueron: el seguimiento previo por un médico internista con OR de 0.07 (IC 95% 0.01-0.35; p = 0.01) y por un endocrinólogo con OR de 0.01 (IC 95% 0.00-0.40; p = 0.02). Conclusiones: los factores de riesgo de hipoglucemia grave fueron: edad, evento previo de hipoglucemia, administración de insulina NPH y secretagogos. De manera interesante, el nivel de especialización del médico en el tratamiento de los pacientes con diabetes mellitus tuvo un papel importante en la reducción del riesgo de hipoglucemia. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Medicina Interna de México is the property of Colegio de Medicina Interna de Mexico and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Languages: – Code: spa Text: Spanish PhysicalDescription: Pagination: PageCount: 12 StartPage: 407 Subjects: – SubjectFull: ENDOCRINOLOGY Type: general – SubjectFull: HYPOGLYCEMIA Type: general – SubjectFull: PEOPLE with diabetes Type: general – SubjectFull: CASE-control method Type: general – SubjectFull: LOGISTIC regression analysis Type: general – SubjectFull: DISEASES Type: general – SubjectFull: DISEASE risk factors Type: general Titles: – TitleFull: Factores de riesgo asociados con episodios de hipoglucemia grave en pacientes diabéticos. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Dehesa-López, Edgar – PersonEntity: Name: NameFull: Manzanarez-Moreno, Ismaldo – PersonEntity: Name: NameFull: Quintero-Pérez, Alberto IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: jul-ago2014 Type: published Y: 2014 Identifiers: – Type: issn-print Value: 01864866 Numbering: – Type: volume Value: 30 – Type: issue Value: 4 Titles: – TitleFull: Medicina Interna de México Type: main |
| ResultId | 1 |
