Site-directed mutagenesis of the 5-HT1B receptor increases the affinity of 5-HT for the agonist low-affinity conformation and reduces the intrinsic activity of 5-HT.

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Bibliographic Details
Title: Site-directed mutagenesis of the 5-HT1B receptor increases the affinity of 5-HT for the agonist low-affinity conformation and reduces the intrinsic activity of 5-HT.
Authors: Grånäs C; Department of Neuroscience, Unit of Pharmacology, Uppsala University, Box 593, SE-751 24, Uppsala, Sweden. cgranas@mfi.ku.dk, Nordquist J, Mohell N, Larhammar D
Source: European journal of pharmacology [Eur J Pharmacol] 2001 Jun 08; Vol. 421 (2), pp. 69-76.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print Cited Medium: Print ISSN: 0014-2999 (Print) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:0014-2999
DOI:10.1016/s0014-2999(01)01027-5