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Evaluation of amino acid-based linkers in potent macrocyclic inhibitors of farnesyl-protein transferase.

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Title: Evaluation of amino acid-based linkers in potent macrocyclic inhibitors of farnesyl-protein transferase.
Authors: Beshore DC; Department of Medicinal Chemistry, Merck Research Laboratories, PA 19486, West Point, USA. douglas_beshore@merck.com, Bell IM, Dinsmore CJ, Homnick CF, Culberson JC, Robinson RG, Fernandes C, Walsh ES, Abrams MT, Bhimnathwala HG, Davide JP, Ellis-Hutchings MS, Huber HA, Koblan KS, Buser CA, Kohl NE, Lobell RB, Chen IW, McLoughlin DA, Olah TV, Graham SL, Hartman GD, Williams TM
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2001 Jul 23; Vol. 11 (14), pp. 1817-21.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print Cited Medium: Print ISSN: 0960-894X (Print) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Evaluation of amino acid-based linkers in potent macrocyclic inhibitors of farnesyl-protein transferase.
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  Data: <searchLink fieldCode="AU" term="%22Beshore+DC%22">Beshore DC</searchLink>; Department of Medicinal Chemistry, Merck Research Laboratories, PA 19486, West Point, USA. douglas_beshore@merck.com<br /><searchLink fieldCode="AU" term="%22Bell+IM%22">Bell IM</searchLink><br /><searchLink fieldCode="AU" term="%22Dinsmore+CJ%22">Dinsmore CJ</searchLink><br /><searchLink fieldCode="AU" term="%22Homnick+CF%22">Homnick CF</searchLink><br /><searchLink fieldCode="AU" term="%22Culberson+JC%22">Culberson JC</searchLink><br /><searchLink fieldCode="AU" term="%22Robinson+RG%22">Robinson RG</searchLink><br /><searchLink fieldCode="AU" term="%22Fernandes+C%22">Fernandes C</searchLink><br /><searchLink fieldCode="AU" term="%22Walsh+ES%22">Walsh ES</searchLink><br /><searchLink fieldCode="AU" term="%22Abrams+MT%22">Abrams MT</searchLink><br /><searchLink fieldCode="AU" term="%22Bhimnathwala+HG%22">Bhimnathwala HG</searchLink><br /><searchLink fieldCode="AU" term="%22Davide+JP%22">Davide JP</searchLink><br /><searchLink fieldCode="AU" term="%22Ellis-Hutchings+MS%22">Ellis-Hutchings MS</searchLink><br /><searchLink fieldCode="AU" term="%22Huber+HA%22">Huber HA</searchLink><br /><searchLink fieldCode="AU" term="%22Koblan+KS%22">Koblan KS</searchLink><br /><searchLink fieldCode="AU" term="%22Buser+CA%22">Buser CA</searchLink><br /><searchLink fieldCode="AU" term="%22Kohl+NE%22">Kohl NE</searchLink><br /><searchLink fieldCode="AU" term="%22Lobell+RB%22">Lobell RB</searchLink><br /><searchLink fieldCode="AU" term="%22Chen+IW%22">Chen IW</searchLink><br /><searchLink fieldCode="AU" term="%22McLoughlin+DA%22">McLoughlin DA</searchLink><br /><searchLink fieldCode="AU" term="%22Olah+TV%22">Olah TV</searchLink><br /><searchLink fieldCode="AU" term="%22Graham+SL%22">Graham SL</searchLink><br /><searchLink fieldCode="AU" term="%22Hartman+GD%22">Hartman GD</searchLink><br /><searchLink fieldCode="AU" term="%22Williams+TM%22">Williams TM</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229107377%22">Bioorganic & medicinal chemistry letters</searchLink> [Bioorg Med Chem Lett] 2001 Jul 23; Vol. 11 (14), pp. 1817-21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ltd%22">Elsevier Science Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9107377 <i>Publication Model: </i>Print <i>Cited Medium: </i>Print <i>ISSN: </i>0960-894X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220960894X%22">0960894X </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Med Chem Lett <i>Subsets: </i>MEDLINE
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              Text: 2001 Jul 23
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