View in EDS

10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway.

Saved in:
Bibliographic Details
Title: 10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway.
Authors: Marsilje TH; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA., Labroli MA, Hedrick MP, Jin Q, Desharnais J, Baker SJ, Gooljarsingh LT, Ramcharan J, Tavassoli A, Zhang Y, Wilson IA, Beardsley GP, Benkovic SJ, Boger DL
Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2002 Aug; Vol. 10 (8), pp. 2739-49.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print Cited Medium: Print ISSN: 0968-0896 (Print) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 12057663
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: 10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Marsilje+TH%22">Marsilje TH</searchLink>; Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.<br /><searchLink fieldCode="AU" term="%22Labroli+MA%22">Labroli MA</searchLink><br /><searchLink fieldCode="AU" term="%22Hedrick+MP%22">Hedrick MP</searchLink><br /><searchLink fieldCode="AU" term="%22Jin+Q%22">Jin Q</searchLink><br /><searchLink fieldCode="AU" term="%22Desharnais+J%22">Desharnais J</searchLink><br /><searchLink fieldCode="AU" term="%22Baker+SJ%22">Baker SJ</searchLink><br /><searchLink fieldCode="AU" term="%22Gooljarsingh+LT%22">Gooljarsingh LT</searchLink><br /><searchLink fieldCode="AU" term="%22Ramcharan+J%22">Ramcharan J</searchLink><br /><searchLink fieldCode="AU" term="%22Tavassoli+A%22">Tavassoli A</searchLink><br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink><br /><searchLink fieldCode="AU" term="%22Wilson+IA%22">Wilson IA</searchLink><br /><searchLink fieldCode="AU" term="%22Beardsley+GP%22">Beardsley GP</searchLink><br /><searchLink fieldCode="AU" term="%22Benkovic+SJ%22">Benkovic SJ</searchLink><br /><searchLink fieldCode="AU" term="%22Boger+DL%22">Boger DL</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%229413298%22">Bioorganic & medicinal chemistry</searchLink> [Bioorg Med Chem] 2002 Aug; Vol. 10 (8), pp. 2739-49.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9413298 <i>Publication Model: </i>Print <i>Cited Medium: </i>Print <i>ISSN: </i>0968-0896 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209680896%22">09680896 </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Med Chem <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=12057663
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/s0968-0896(02)00102-5
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 2739
    Titles:
      – TitleFull: 10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Marsilje TH
      – PersonEntity:
          Name:
            NameFull: Labroli MA
      – PersonEntity:
          Name:
            NameFull: Hedrick MP
      – PersonEntity:
          Name:
            NameFull: Jin Q
      – PersonEntity:
          Name:
            NameFull: Desharnais J
      – PersonEntity:
          Name:
            NameFull: Baker SJ
      – PersonEntity:
          Name:
            NameFull: Gooljarsingh LT
      – PersonEntity:
          Name:
            NameFull: Ramcharan J
      – PersonEntity:
          Name:
            NameFull: Tavassoli A
      – PersonEntity:
          Name:
            NameFull: Zhang Y
      – PersonEntity:
          Name:
            NameFull: Wilson IA
      – PersonEntity:
          Name:
            NameFull: Beardsley GP
      – PersonEntity:
          Name:
            NameFull: Benkovic SJ
      – PersonEntity:
          Name:
            NameFull: Boger DL
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 08
              Text: 2002 Aug
              Type: published
              Y: 2002
          Identifiers:
            – Type: issn-print
              Value: 0968-0896
          Numbering:
            – Type: volume
              Value: 10
            – Type: issue
              Value: 8
          Titles:
            – TitleFull: Bioorganic & medicinal chemistry
              Type: main
ResultId 1