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Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954).

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Title: Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954).
Authors: Croston GE; ACADIA Pharmaceuticals Inc., 3911 Sorrento Valley Boulevard, San Diego, California 92121, USA., Olsson R, Currier EA, Burstein ES, Weiner D, Nash N, Severance D, Allenmark SG, Thunberg L, Ma JN, Mohell N, O'Dowd B, Brann MR, Hacksell U
Source: Journal of medicinal chemistry [J Med Chem] 2002 Nov 07; Vol. 45 (23), pp. 4950-3.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954).
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  Data: <searchLink fieldCode="AU" term="%22Croston+GE%22">Croston GE</searchLink>; ACADIA Pharmaceuticals Inc., 3911 Sorrento Valley Boulevard, San Diego, California 92121, USA.<br /><searchLink fieldCode="AU" term="%22Olsson+R%22">Olsson R</searchLink><br /><searchLink fieldCode="AU" term="%22Currier+EA%22">Currier EA</searchLink><br /><searchLink fieldCode="AU" term="%22Burstein+ES%22">Burstein ES</searchLink><br /><searchLink fieldCode="AU" term="%22Weiner+D%22">Weiner D</searchLink><br /><searchLink fieldCode="AU" term="%22Nash+N%22">Nash N</searchLink><br /><searchLink fieldCode="AU" term="%22Severance+D%22">Severance D</searchLink><br /><searchLink fieldCode="AU" term="%22Allenmark+SG%22">Allenmark SG</searchLink><br /><searchLink fieldCode="AU" term="%22Thunberg+L%22">Thunberg L</searchLink><br /><searchLink fieldCode="AU" term="%22Ma+JN%22">Ma JN</searchLink><br /><searchLink fieldCode="AU" term="%22Mohell+N%22">Mohell N</searchLink><br /><searchLink fieldCode="AU" term="%22O'Dowd+B%22">O'Dowd B</searchLink><br /><searchLink fieldCode="AU" term="%22Brann+MR%22">Brann MR</searchLink><br /><searchLink fieldCode="AU" term="%22Hacksell+U%22">Hacksell U</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2002 Nov 07; Vol. 45 (23), pp. 4950-3.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print <i>Cited Medium: </i>Print <i>ISSN: </i>0022-2623 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=12408704
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        Value: 10.1021/jm025551+
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        Text: English
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        StartPage: 4950
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      – TitleFull: Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954).
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              Text: 2002 Nov 07
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