Human SPF45, a splicing factor, has limited expression in normal tissues, is overexpressed in many tumors, and can confer a multidrug-resistant phenotype to cells. - Sampath J; Long PR; Shepard RL; Xia X; Devanarayan V; Sandusky GE; Perry WL 3rd; Dantzig AH; Williamson M; Rolfe M; Moore RE (The American journal of pathology, 2003)