Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging. - Van Remmen H; Ikeno Y; Hamilton M; Pahlavani M; Wolf N; Thorpe SR; Alderson NL; Baynes JW; Epstein CJ; Huang TT; Nelson J; Strong R; et al. (Physiological genomics, 2003)