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Substituted 3-imidazo[1,2-a]pyridin-3-yl- 4-(1,2,3,4-tetrahydro-[1,4]diazepino-[6,7,1-hi]indol-7-yl)pyrrole-2,5-diones as highly selective and potent inhibitors of glycogen synthase kinase-3.

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Title: Substituted 3-imidazo[1,2-a]pyridin-3-yl- 4-(1,2,3,4-tetrahydro-[1,4]diazepino-[6,7,1-hi]indol-7-yl)pyrrole-2,5-diones as highly selective and potent inhibitors of glycogen synthase kinase-3.
Authors: Engler TA; Lilly Research Laboratories, A Division of Eli Lilly & Company, Lilly Corporate Center, Indianapolis, Indiana 46285, USA. Engler_Thomas@lilly.com, Henry JR, Malhotra S, Cunningham B, Furness K, Brozinick J, Burkholder TP, Clay MP, Clayton J, Diefenbacher C, Hawkins E, Iversen PW, Li Y, Lindstrom TD, Marquart AL, McLean J, Mendel D, Misener E, Briere D, O'Toole JC, Porter WJ, Queener S, Reel JK, Owens RA, Brier RA, Eessalu TE, Wagner JR, Campbell RM, Vaughn R
Source: Journal of medicinal chemistry [J Med Chem] 2004 Jul 29; Vol. 47 (16), pp. 3934-7.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print Cited Medium: Print ISSN: 0022-2623 (Print) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Substituted 3-imidazo[1,2-a]pyridin-3-yl- 4-(1,2,3,4-tetrahydro-[1,4]diazepino-[6,7,1-hi]indol-7-yl)pyrrole-2,5-diones as highly selective and potent inhibitors of glycogen synthase kinase-3.
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  Data: <searchLink fieldCode="AU" term="%22Engler+TA%22">Engler TA</searchLink>; Lilly Research Laboratories, A Division of Eli Lilly & Company, Lilly Corporate Center, Indianapolis, Indiana 46285, USA. Engler_Thomas@lilly.com<br /><searchLink fieldCode="AU" term="%22Henry+JR%22">Henry JR</searchLink><br /><searchLink fieldCode="AU" term="%22Malhotra+S%22">Malhotra S</searchLink><br /><searchLink fieldCode="AU" term="%22Cunningham+B%22">Cunningham B</searchLink><br /><searchLink fieldCode="AU" term="%22Furness+K%22">Furness K</searchLink><br /><searchLink fieldCode="AU" term="%22Brozinick+J%22">Brozinick J</searchLink><br /><searchLink fieldCode="AU" term="%22Burkholder+TP%22">Burkholder TP</searchLink><br /><searchLink fieldCode="AU" term="%22Clay+MP%22">Clay MP</searchLink><br /><searchLink fieldCode="AU" term="%22Clayton+J%22">Clayton J</searchLink><br /><searchLink fieldCode="AU" term="%22Diefenbacher+C%22">Diefenbacher C</searchLink><br /><searchLink fieldCode="AU" term="%22Hawkins+E%22">Hawkins E</searchLink><br /><searchLink fieldCode="AU" term="%22Iversen+PW%22">Iversen PW</searchLink><br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink><br /><searchLink fieldCode="AU" term="%22Lindstrom+TD%22">Lindstrom TD</searchLink><br /><searchLink fieldCode="AU" term="%22Marquart+AL%22">Marquart AL</searchLink><br /><searchLink fieldCode="AU" term="%22McLean+J%22">McLean J</searchLink><br /><searchLink fieldCode="AU" term="%22Mendel+D%22">Mendel D</searchLink><br /><searchLink fieldCode="AU" term="%22Misener+E%22">Misener E</searchLink><br /><searchLink fieldCode="AU" term="%22Briere+D%22">Briere D</searchLink><br /><searchLink fieldCode="AU" term="%22O'Toole+JC%22">O'Toole JC</searchLink><br /><searchLink fieldCode="AU" term="%22Porter+WJ%22">Porter WJ</searchLink><br /><searchLink fieldCode="AU" term="%22Queener+S%22">Queener S</searchLink><br /><searchLink fieldCode="AU" term="%22Reel+JK%22">Reel JK</searchLink><br /><searchLink fieldCode="AU" term="%22Owens+RA%22">Owens RA</searchLink><br /><searchLink fieldCode="AU" term="%22Brier+RA%22">Brier RA</searchLink><br /><searchLink fieldCode="AU" term="%22Eessalu+TE%22">Eessalu TE</searchLink><br /><searchLink fieldCode="AU" term="%22Wagner+JR%22">Wagner JR</searchLink><br /><searchLink fieldCode="AU" term="%22Campbell+RM%22">Campbell RM</searchLink><br /><searchLink fieldCode="AU" term="%22Vaughn+R%22">Vaughn R</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2004 Jul 29; Vol. 47 (16), pp. 3934-7.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print <i>Cited Medium: </i>Print <i>ISSN: </i>0022-2623 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE
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