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The synthesis and structure-activity relationship studies of selective acetyl-CoA carboxylase inhibitors containing 4-(thiazol-5-yl)but-3-yn-2-amino motif: polar region modifications.

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Title: The synthesis and structure-activity relationship studies of selective acetyl-CoA carboxylase inhibitors containing 4-(thiazol-5-yl)but-3-yn-2-amino motif: polar region modifications.
Authors: Xu X; Metabolic Disease Research, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL 60064, USA. xiangdong.xu@abbott.com, Weitzberg M, Keyes RF, Li Q, Wang R, Wang X, Zhang X, Frevert EU, Camp HS, Beutel BA, Sham HL, Gu YG
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2007 Mar 15; Vol. 17 (6), pp. 1803-7. Date of Electronic Publication: 2006 Dec 21.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0960-894X (Print) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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An: 17234407
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: The synthesis and structure-activity relationship studies of selective acetyl-CoA carboxylase inhibitors containing 4-(thiazol-5-yl)but-3-yn-2-amino motif: polar region modifications.
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  Data: <searchLink fieldCode="AU" term="%22Xu+X%22">Xu X</searchLink>; Metabolic Disease Research, Global Pharmaceutical Research and Development, Abbott Laboratories, Abbott Park, IL 60064, USA. xiangdong.xu@abbott.com<br /><searchLink fieldCode="AU" term="%22Weitzberg+M%22">Weitzberg M</searchLink><br /><searchLink fieldCode="AU" term="%22Keyes+RF%22">Keyes RF</searchLink><br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink><br /><searchLink fieldCode="AU" term="%22Wang+R%22">Wang R</searchLink><br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink><br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink><br /><searchLink fieldCode="AU" term="%22Frevert+EU%22">Frevert EU</searchLink><br /><searchLink fieldCode="AU" term="%22Camp+HS%22">Camp HS</searchLink><br /><searchLink fieldCode="AU" term="%22Beutel+BA%22">Beutel BA</searchLink><br /><searchLink fieldCode="AU" term="%22Sham+HL%22">Sham HL</searchLink><br /><searchLink fieldCode="AU" term="%22Gu+YG%22">Gu YG</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229107377%22">Bioorganic & medicinal chemistry letters</searchLink> [Bioorg Med Chem Lett] 2007 Mar 15; Vol. 17 (6), pp. 1803-7. <i>Date of Electronic Publication: </i>2006 Dec 21.
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        Value: 10.1016/j.bmcl.2006.12.047
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              Text: 2007 Mar 15
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