Next-generation spirobenzazepines: identification of RWJ-676070 as a balanced vasopressin V1a/V2 receptor antagonist for human clinical studies. - Xiang MA; Rybczynski PJ; Patel M; Chen RH; McComsey DF; Zhang HC; Gunnet JW; Look R; Wang Y; Minor LK; Zhong HM; Villani FJ; et al. (Bioorganic & medicinal chemistry letters, 2007)