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Potent and orally bioavailable zwitterion GnRH antagonists with low CYP3A4 inhibitory activity.

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Title: Potent and orally bioavailable zwitterion GnRH antagonists with low CYP3A4 inhibitory activity.
Authors: Chen C; Department of Medicinal Chemistry, Neurocrine Biosciences, Inc., 12790 El Camino Real, San Diego, CA 92130, USA. cchen@neurocrine.com, Chen Y, Pontillo J, Guo Z, Huang CQ, Wu D, Madan A, Chen T, Wen J, Xie Q, Tucci FC, Rowbottom M, Zhu YF, Wade W, Saunders J, Bozigian H, Struthers RS
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2008 Jun 01; Vol. 18 (11), pp. 3301-5. Date of Electronic Publication: 2008 Apr 26.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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An: 18442910
AccessLevel: 2
PubType: Academic Journal
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  Data: Potent and orally bioavailable zwitterion GnRH antagonists with low CYP3A4 inhibitory activity.
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  Data: <searchLink fieldCode="AU" term="%22Chen+C%22">Chen C</searchLink>; Department of Medicinal Chemistry, Neurocrine Biosciences, Inc., 12790 El Camino Real, San Diego, CA 92130, USA. cchen@neurocrine.com<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink><br /><searchLink fieldCode="AU" term="%22Pontillo+J%22">Pontillo J</searchLink><br /><searchLink fieldCode="AU" term="%22Guo+Z%22">Guo Z</searchLink><br /><searchLink fieldCode="AU" term="%22Huang+CQ%22">Huang CQ</searchLink><br /><searchLink fieldCode="AU" term="%22Wu+D%22">Wu D</searchLink><br /><searchLink fieldCode="AU" term="%22Madan+A%22">Madan A</searchLink><br /><searchLink fieldCode="AU" term="%22Chen+T%22">Chen T</searchLink><br /><searchLink fieldCode="AU" term="%22Wen+J%22">Wen J</searchLink><br /><searchLink fieldCode="AU" term="%22Xie+Q%22">Xie Q</searchLink><br /><searchLink fieldCode="AU" term="%22Tucci+FC%22">Tucci FC</searchLink><br /><searchLink fieldCode="AU" term="%22Rowbottom+M%22">Rowbottom M</searchLink><br /><searchLink fieldCode="AU" term="%22Zhu+YF%22">Zhu YF</searchLink><br /><searchLink fieldCode="AU" term="%22Wade+W%22">Wade W</searchLink><br /><searchLink fieldCode="AU" term="%22Saunders+J%22">Saunders J</searchLink><br /><searchLink fieldCode="AU" term="%22Bozigian+H%22">Bozigian H</searchLink><br /><searchLink fieldCode="AU" term="%22Struthers+RS%22">Struthers RS</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229107377%22">Bioorganic & medicinal chemistry letters</searchLink> [Bioorg Med Chem Lett] 2008 Jun 01; Vol. 18 (11), pp. 3301-5. <i>Date of Electronic Publication: </i>2008 Apr 26.
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        Value: 10.1016/j.bmcl.2008.04.036
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              Text: 2008 Jun 01
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