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Zwitterionic uracil derivatives as potent GnRH receptor antagonists with improved pharmaceutical properties.

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Title: Zwitterionic uracil derivatives as potent GnRH receptor antagonists with improved pharmaceutical properties.
Authors: Regan CF; Department of Medicinal Chemistry, Neurocrine Biosciences, Inc., 12780 El Camino Real, San Diego, CA 92130, USA., Guo Z, Chen Y, Huang CQ, Chen M, Jiang W, Rueter JK, Coon T, Chen C, Saunders J, Brown MS, Betz SF, Struthers RS, Yang C, Wen J, Madan A, Zhu YF
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2008 Aug 15; Vol. 18 (16), pp. 4503-7. Date of Electronic Publication: 2008 Jul 17.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 18667310
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Zwitterionic uracil derivatives as potent GnRH receptor antagonists with improved pharmaceutical properties.
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  Data: <searchLink fieldCode="AU" term="%22Regan+CF%22">Regan CF</searchLink>; Department of Medicinal Chemistry, Neurocrine Biosciences, Inc., 12780 El Camino Real, San Diego, CA 92130, USA.<br /><searchLink fieldCode="AU" term="%22Guo+Z%22">Guo Z</searchLink><br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink><br /><searchLink fieldCode="AU" term="%22Huang+CQ%22">Huang CQ</searchLink><br /><searchLink fieldCode="AU" term="%22Chen+M%22">Chen M</searchLink><br /><searchLink fieldCode="AU" term="%22Jiang+W%22">Jiang W</searchLink><br /><searchLink fieldCode="AU" term="%22Rueter+JK%22">Rueter JK</searchLink><br /><searchLink fieldCode="AU" term="%22Coon+T%22">Coon T</searchLink><br /><searchLink fieldCode="AU" term="%22Chen+C%22">Chen C</searchLink><br /><searchLink fieldCode="AU" term="%22Saunders+J%22">Saunders J</searchLink><br /><searchLink fieldCode="AU" term="%22Brown+MS%22">Brown MS</searchLink><br /><searchLink fieldCode="AU" term="%22Betz+SF%22">Betz SF</searchLink><br /><searchLink fieldCode="AU" term="%22Struthers+RS%22">Struthers RS</searchLink><br /><searchLink fieldCode="AU" term="%22Yang+C%22">Yang C</searchLink><br /><searchLink fieldCode="AU" term="%22Wen+J%22">Wen J</searchLink><br /><searchLink fieldCode="AU" term="%22Madan+A%22">Madan A</searchLink><br /><searchLink fieldCode="AU" term="%22Zhu+YF%22">Zhu YF</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229107377%22">Bioorganic & medicinal chemistry letters</searchLink> [Bioorg Med Chem Lett] 2008 Aug 15; Vol. 18 (16), pp. 4503-7. <i>Date of Electronic Publication: </i>2008 Jul 17.
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        Value: 10.1016/j.bmcl.2008.07.059
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        Text: English
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        StartPage: 4503
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              Text: 2008 Aug 15
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