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Structure-guided design of substituted aza-benzimidazoles as potent hypoxia inducible factor-1alpha prolyl hydroxylase-2 inhibitors.

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Title: Structure-guided design of substituted aza-benzimidazoles as potent hypoxia inducible factor-1alpha prolyl hydroxylase-2 inhibitors.
Authors: Frohn M; Department of Chemistry Research and Discovery, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA. mfrohn@amgen.com, Viswanadhan V, Pickrell AJ, Golden JE, Muller KM, Bürli RW, Biddlecome G, Yoder SC, Rogers N, Dao JH, Hungate R, Allen JR
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2008 Sep 15; Vol. 18 (18), pp. 5023-6. Date of Electronic Publication: 2008 Aug 09.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Structure-guided design of substituted aza-benzimidazoles as potent hypoxia inducible factor-1alpha prolyl hydroxylase-2 inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Frohn+M%22">Frohn M</searchLink>; Department of Chemistry Research and Discovery, Amgen, Inc., One Amgen Center Drive, Thousand Oaks, CA 91320, USA. mfrohn@amgen.com<br /><searchLink fieldCode="AU" term="%22Viswanadhan+V%22">Viswanadhan V</searchLink><br /><searchLink fieldCode="AU" term="%22Pickrell+AJ%22">Pickrell AJ</searchLink><br /><searchLink fieldCode="AU" term="%22Golden+JE%22">Golden JE</searchLink><br /><searchLink fieldCode="AU" term="%22Muller+KM%22">Muller KM</searchLink><br /><searchLink fieldCode="AU" term="%22Bürli+RW%22">Bürli RW</searchLink><br /><searchLink fieldCode="AU" term="%22Biddlecome+G%22">Biddlecome G</searchLink><br /><searchLink fieldCode="AU" term="%22Yoder+SC%22">Yoder SC</searchLink><br /><searchLink fieldCode="AU" term="%22Rogers+N%22">Rogers N</searchLink><br /><searchLink fieldCode="AU" term="%22Dao+JH%22">Dao JH</searchLink><br /><searchLink fieldCode="AU" term="%22Hungate+R%22">Hungate R</searchLink><br /><searchLink fieldCode="AU" term="%22Allen+JR%22">Allen JR</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229107377%22">Bioorganic & medicinal chemistry letters</searchLink> [Bioorg Med Chem Lett] 2008 Sep 15; Vol. 18 (18), pp. 5023-6. <i>Date of Electronic Publication: </i>2008 Aug 09.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ltd%22">Elsevier Science Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9107377 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1464-3405 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220960894X%22">0960894X </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Med Chem Lett <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bmcl.2008.08.012
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              Text: 2008 Sep 15
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