Identification and synthesis of 2,7-diamino-thiazolo[5,4-d]pyrimidine derivatives as TRPV1 antagonists.

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Title: Identification and synthesis of 2,7-diamino-thiazolo[5,4-d]pyrimidine derivatives as TRPV1 antagonists.
Authors: Lebsack AD; Johnson & Johnson Pharmaceutical Research and Development LLC, San Diego, CA 92121, USA. alebsack@its.jnj.com, Branstetter BJ, Hack MD, Xiao W, Peterson ML, Nasser N, Maher MP, Ao H, Bhattacharya A, Kansagara M, Scott BP, Luo L, Rynberg R, Rizzolio M, Chaplan SR, Wickenden AD, Guy Breitenbucher J
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2009 Jan 01; Vol. 19 (1), pp. 40-6. Date of Electronic Publication: 2008 Nov 13.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
An: 19038548
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PubType: Academic Journal
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  Data: Identification and synthesis of 2,7-diamino-thiazolo[5,4-d]pyrimidine derivatives as TRPV1 antagonists.
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  Data: <searchLink fieldCode="AU" term="%22Lebsack+AD%22">Lebsack AD</searchLink>; Johnson & Johnson Pharmaceutical Research and Development LLC, San Diego, CA 92121, USA. alebsack@its.jnj.com<br /><searchLink fieldCode="AU" term="%22Branstetter+BJ%22">Branstetter BJ</searchLink><br /><searchLink fieldCode="AU" term="%22Hack+MD%22">Hack MD</searchLink><br /><searchLink fieldCode="AU" term="%22Xiao+W%22">Xiao W</searchLink><br /><searchLink fieldCode="AU" term="%22Peterson+ML%22">Peterson ML</searchLink><br /><searchLink fieldCode="AU" term="%22Nasser+N%22">Nasser N</searchLink><br /><searchLink fieldCode="AU" term="%22Maher+MP%22">Maher MP</searchLink><br /><searchLink fieldCode="AU" term="%22Ao+H%22">Ao H</searchLink><br /><searchLink fieldCode="AU" term="%22Bhattacharya+A%22">Bhattacharya A</searchLink><br /><searchLink fieldCode="AU" term="%22Kansagara+M%22">Kansagara M</searchLink><br /><searchLink fieldCode="AU" term="%22Scott+BP%22">Scott BP</searchLink><br /><searchLink fieldCode="AU" term="%22Luo+L%22">Luo L</searchLink><br /><searchLink fieldCode="AU" term="%22Rynberg+R%22">Rynberg R</searchLink><br /><searchLink fieldCode="AU" term="%22Rizzolio+M%22">Rizzolio M</searchLink><br /><searchLink fieldCode="AU" term="%22Chaplan+SR%22">Chaplan SR</searchLink><br /><searchLink fieldCode="AU" term="%22Wickenden+AD%22">Wickenden AD</searchLink><br /><searchLink fieldCode="AU" term="%22Guy+Breitenbucher+J%22">Guy Breitenbucher J</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229107377%22">Bioorganic & medicinal chemistry letters</searchLink> [Bioorg Med Chem Lett] 2009 Jan 01; Vol. 19 (1), pp. 40-6. <i>Date of Electronic Publication: </i>2008 Nov 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ltd%22">Elsevier Science Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9107377 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1464-3405 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220960894X%22">0960894X </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Med Chem Lett <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bmcl.2008.11.024
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              Text: 2009 Jan 01
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