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Synthesis and biological evaluation of ((4-keto)-phenoxy)methyl biphenyl-4-sulfonamides: a class of potent aggrecanase-1 inhibitors.

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Title: Synthesis and biological evaluation of ((4-keto)-phenoxy)methyl biphenyl-4-sulfonamides: a class of potent aggrecanase-1 inhibitors.
Authors: Hopper DW; Department of Chemical and Screening Sciences, Wyeth Research, 401 North Middletown Road, Pearl River, NY 10965, USA., Vera MD, How D, Sabatini J, Xiang JS, Ipek M, Thomason J, Hu Y, Feyfant E, Wang Q, Georgiadis KE, Reifenberg E, Sheldon RT, Keohan CC, Majumdar MK, Morris EA, Skotnicki J, Sum PE
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2009 May 01; Vol. 19 (9), pp. 2487-91. Date of Electronic Publication: 2009 Mar 18.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 19329309
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Synthesis and biological evaluation of ((4-keto)-phenoxy)methyl biphenyl-4-sulfonamides: a class of potent aggrecanase-1 inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Hopper+DW%22">Hopper DW</searchLink>; Department of Chemical and Screening Sciences, Wyeth Research, 401 North Middletown Road, Pearl River, NY 10965, USA.<br /><searchLink fieldCode="AU" term="%22Vera+MD%22">Vera MD</searchLink><br /><searchLink fieldCode="AU" term="%22How+D%22">How D</searchLink><br /><searchLink fieldCode="AU" term="%22Sabatini+J%22">Sabatini J</searchLink><br /><searchLink fieldCode="AU" term="%22Xiang+JS%22">Xiang JS</searchLink><br /><searchLink fieldCode="AU" term="%22Ipek+M%22">Ipek M</searchLink><br /><searchLink fieldCode="AU" term="%22Thomason+J%22">Thomason J</searchLink><br /><searchLink fieldCode="AU" term="%22Hu+Y%22">Hu Y</searchLink><br /><searchLink fieldCode="AU" term="%22Feyfant+E%22">Feyfant E</searchLink><br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink><br /><searchLink fieldCode="AU" term="%22Georgiadis+KE%22">Georgiadis KE</searchLink><br /><searchLink fieldCode="AU" term="%22Reifenberg+E%22">Reifenberg E</searchLink><br /><searchLink fieldCode="AU" term="%22Sheldon+RT%22">Sheldon RT</searchLink><br /><searchLink fieldCode="AU" term="%22Keohan+CC%22">Keohan CC</searchLink><br /><searchLink fieldCode="AU" term="%22Majumdar+MK%22">Majumdar MK</searchLink><br /><searchLink fieldCode="AU" term="%22Morris+EA%22">Morris EA</searchLink><br /><searchLink fieldCode="AU" term="%22Skotnicki+J%22">Skotnicki J</searchLink><br /><searchLink fieldCode="AU" term="%22Sum+PE%22">Sum PE</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229107377%22">Bioorganic & medicinal chemistry letters</searchLink> [Bioorg Med Chem Lett] 2009 May 01; Vol. 19 (9), pp. 2487-91. <i>Date of Electronic Publication: </i>2009 Mar 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ltd%22">Elsevier Science Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9107377 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1464-3405 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220960894X%22">0960894X </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Med Chem Lett <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=19329309
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        Value: 10.1016/j.bmcl.2009.03.056
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        Text: English
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              Text: 2009 May 01
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