Hepatic ceramide may mediate brain insulin resistance and neurodegeneration in type 2 diabetes and non-alcoholic steatohepatitis. - Lyn-Cook LE Jr; Lawton M; Tong M; Silbermann E; Longato L; Jiao P; Mark P; Wands JR; Xu H; de la Monte SM (Journal of Alzheimer's disease : JAD, 2009)