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Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia.

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Title: Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia.
Authors: Tammam J; Department of Oncology/Pharmacology, Merck Research Laboratories, Boston, MA 02115, USA., Ware C, Efferson C, O'Neil J, Rao S, Qu X, Gorenstein J, Angagaw M, Kim H, Kenific C, Kunii K, Leach KJ, Nikov G, Zhao J, Dai X, Hardwick J, Scott M, Winter C, Bristow L, Elbi C, Reilly JF, Look T, Draetta G, Van der Ploeg L, Kohl NE, Strack PR, Majumder PK
Source: British journal of pharmacology [Br J Pharmacol] 2009 Nov; Vol. 158 (5), pp. 1183-95. Date of Electronic Publication: 2009 Sep 23.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Tammam+J%22">Tammam J</searchLink>; Department of Oncology/Pharmacology, Merck Research Laboratories, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Ware+C%22">Ware C</searchLink><br /><searchLink fieldCode="AU" term="%22Efferson+C%22">Efferson C</searchLink><br /><searchLink fieldCode="AU" term="%22O'Neil+J%22">O'Neil J</searchLink><br /><searchLink fieldCode="AU" term="%22Rao+S%22">Rao S</searchLink><br /><searchLink fieldCode="AU" term="%22Qu+X%22">Qu X</searchLink><br /><searchLink fieldCode="AU" term="%22Gorenstein+J%22">Gorenstein J</searchLink><br /><searchLink fieldCode="AU" term="%22Angagaw+M%22">Angagaw M</searchLink><br /><searchLink fieldCode="AU" term="%22Kim+H%22">Kim H</searchLink><br /><searchLink fieldCode="AU" term="%22Kenific+C%22">Kenific C</searchLink><br /><searchLink fieldCode="AU" term="%22Kunii+K%22">Kunii K</searchLink><br /><searchLink fieldCode="AU" term="%22Leach+KJ%22">Leach KJ</searchLink><br /><searchLink fieldCode="AU" term="%22Nikov+G%22">Nikov G</searchLink><br /><searchLink fieldCode="AU" term="%22Zhao+J%22">Zhao J</searchLink><br /><searchLink fieldCode="AU" term="%22Dai+X%22">Dai X</searchLink><br /><searchLink fieldCode="AU" term="%22Hardwick+J%22">Hardwick J</searchLink><br /><searchLink fieldCode="AU" term="%22Scott+M%22">Scott M</searchLink><br /><searchLink fieldCode="AU" term="%22Winter+C%22">Winter C</searchLink><br /><searchLink fieldCode="AU" term="%22Bristow+L%22">Bristow L</searchLink><br /><searchLink fieldCode="AU" term="%22Elbi+C%22">Elbi C</searchLink><br /><searchLink fieldCode="AU" term="%22Reilly+JF%22">Reilly JF</searchLink><br /><searchLink fieldCode="AU" term="%22Look+T%22">Look T</searchLink><br /><searchLink fieldCode="AU" term="%22Draetta+G%22">Draetta G</searchLink><br /><searchLink fieldCode="AU" term="%22Van+der+Ploeg+L%22">Van der Ploeg L</searchLink><br /><searchLink fieldCode="AU" term="%22Kohl+NE%22">Kohl NE</searchLink><br /><searchLink fieldCode="AU" term="%22Strack+PR%22">Strack PR</searchLink><br /><searchLink fieldCode="AU" term="%22Majumder+PK%22">Majumder PK</searchLink>
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  Data: <searchLink fieldCode="JN" term="%227502536%22">British journal of pharmacology</searchLink> [Br J Pharmacol] 2009 Nov; Vol. 158 (5), pp. 1183-95. <i>Date of Electronic Publication: </i>2009 Sep 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7502536 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5381 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200071188%22">00071188 </searchLink><i>NLM ISO Abbreviation: </i>Br J Pharmacol <i>Subsets: </i>MEDLINE
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