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Genomic architecture characterizes tumor progression paths and fate in breast cancer patients.

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Title: Genomic architecture characterizes tumor progression paths and fate in breast cancer patients.
Authors: Russnes HG; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.; Division of Pathology, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.; Insitute for Clinical Medicine, Faculty of Medicine, University of Oslo., Vollan HKM; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.; Insitute for Clinical Medicine, Faculty of Medicine, University of Oslo.; Department of Breast and Endocrine Surgery, Division of Surgery and Cancer, Oslo University Hospital, 0450 Oslo, Norway., Lingjærde OC; Biomedical Research Group, Department of Informatics, University of Oslo, P.O. Box 1080 Blindern, 0316 Oslo, Norway., Krasnitz A; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA., Lundin P; Department of Oncology-Pathology, Karolinska Institutet, Cancer Center Karolinska, SE-171 76 Stockholm, Sweden., Naume B; Department of Oncology, Division of Surgery and Cancer, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway., Sørlie T; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway., Borgen E; Division of Pathology, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway., Rye IH; Division of Pathology, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway., Langerød A; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway., Chin SF; Breast Cancer Functional Genomics, Cancer Research UK Cambridge Research Institute and Department of Oncology, University of Cambridge, Li Ka-Shing Centre, Robinson Way, Cambridge CB2 0RE, UK., Teschendorff AE; Breast Cancer Functional Genomics, Cancer Research UK Cambridge Research Institute and Department of Oncology, University of Cambridge, Li Ka-Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.; UCL Cancer Institute, University College London, WC1E 6BT, UK., Stephens PJ; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK., Månér S; Department of Oncology-Pathology, Karolinska Institutet, Cancer Center Karolinska, SE-171 76 Stockholm, Sweden., Schlichting E; Department of Breast and Endocrine Surgery, Division of Surgery and Cancer, Oslo University Hospital, 0450 Oslo, Norway., Baumbusch LO; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.; Division of Pathology, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.; Biomedical Research Group, Department of Informatics, University of Oslo, P.O. Box 1080 Blindern, 0316 Oslo, Norway., Kåresen R; Department of Breast and Endocrine Surgery, Division of Surgery and Cancer, Oslo University Hospital, 0450 Oslo, Norway., Stratton MP; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.; Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK., Wigler M; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA., Caldas C; Breast Cancer Functional Genomics, Cancer Research UK Cambridge Research Institute and Department of Oncology, University of Cambridge, Li Ka-Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.; Cambridge Breast Unit, Addenbrookes Hospital and Cambridge NIHR Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, UK., Zetterberg A; Department of Oncology-Pathology, Karolinska Institutet, Cancer Center Karolinska, SE-171 76 Stockholm, Sweden., Hicks J; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA., Børresen-Dale AL; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.; Insitute for Clinical Medicine, Faculty of Medicine, University of Oslo.
Source: Science translational medicine [Sci Transl Med] 2010 Jun 30; Vol. 2 (38), pp. 38ra47.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Russnes+HG%22">Russnes HG</searchLink>; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.; Division of Pathology, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.; Insitute for Clinical Medicine, Faculty of Medicine, University of Oslo.<br /><searchLink fieldCode="AU" term="%22Vollan+HKM%22">Vollan HKM</searchLink>; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.; Insitute for Clinical Medicine, Faculty of Medicine, University of Oslo.; Department of Breast and Endocrine Surgery, Division of Surgery and Cancer, Oslo University Hospital, 0450 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Lingjærde+OC%22">Lingjærde OC</searchLink>; Biomedical Research Group, Department of Informatics, University of Oslo, P.O. Box 1080 Blindern, 0316 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Krasnitz+A%22">Krasnitz A</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.<br /><searchLink fieldCode="AU" term="%22Lundin+P%22">Lundin P</searchLink>; Department of Oncology-Pathology, Karolinska Institutet, Cancer Center Karolinska, SE-171 76 Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Naume+B%22">Naume B</searchLink>; Department of Oncology, Division of Surgery and Cancer, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Sørlie+T%22">Sørlie T</searchLink>; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Borgen+E%22">Borgen E</searchLink>; Division of Pathology, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Rye+IH%22">Rye IH</searchLink>; Division of Pathology, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Langerød+A%22">Langerød A</searchLink>; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Chin+SF%22">Chin SF</searchLink>; Breast Cancer Functional Genomics, Cancer Research UK Cambridge Research Institute and Department of Oncology, University of Cambridge, Li Ka-Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.<br /><searchLink fieldCode="AU" term="%22Teschendorff+AE%22">Teschendorff AE</searchLink>; Breast Cancer Functional Genomics, Cancer Research UK Cambridge Research Institute and Department of Oncology, University of Cambridge, Li Ka-Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.; UCL Cancer Institute, University College London, WC1E 6BT, UK.<br /><searchLink fieldCode="AU" term="%22Stephens+PJ%22">Stephens PJ</searchLink>; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.<br /><searchLink fieldCode="AU" term="%22Månér+S%22">Månér S</searchLink>; Department of Oncology-Pathology, Karolinska Institutet, Cancer Center Karolinska, SE-171 76 Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Schlichting+E%22">Schlichting E</searchLink>; Department of Breast and Endocrine Surgery, Division of Surgery and Cancer, Oslo University Hospital, 0450 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Baumbusch+LO%22">Baumbusch LO</searchLink>; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.; Division of Pathology, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.; Biomedical Research Group, Department of Informatics, University of Oslo, P.O. Box 1080 Blindern, 0316 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Kåresen+R%22">Kåresen R</searchLink>; Department of Breast and Endocrine Surgery, Division of Surgery and Cancer, Oslo University Hospital, 0450 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Stratton+MP%22">Stratton MP</searchLink>; Cancer Genome Project, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, UK.; Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK.<br /><searchLink fieldCode="AU" term="%22Wigler+M%22">Wigler M</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.<br /><searchLink fieldCode="AU" term="%22Caldas+C%22">Caldas C</searchLink>; Breast Cancer Functional Genomics, Cancer Research UK Cambridge Research Institute and Department of Oncology, University of Cambridge, Li Ka-Shing Centre, Robinson Way, Cambridge CB2 0RE, UK.; Cambridge Breast Unit, Addenbrookes Hospital and Cambridge NIHR Biomedical Research Centre, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Zetterberg+A%22">Zetterberg A</searchLink>; Department of Oncology-Pathology, Karolinska Institutet, Cancer Center Karolinska, SE-171 76 Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Hicks+J%22">Hicks J</searchLink>; Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USA.<br /><searchLink fieldCode="AU" term="%22Børresen-Dale+AL%22">Børresen-Dale AL</searchLink>; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, 0310 Oslo, Norway.; Insitute for Clinical Medicine, Faculty of Medicine, University of Oslo.
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