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A phase I pharmacokinetic and pharmacodynamic study of dalotuzumab (MK-0646), an anti-insulin-like growth factor-1 receptor monoclonal antibody, in patients with advanced solid tumors.

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Title: A phase I pharmacokinetic and pharmacodynamic study of dalotuzumab (MK-0646), an anti-insulin-like growth factor-1 receptor monoclonal antibody, in patients with advanced solid tumors.
Authors: Atzori F; Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain., Tabernero J, Cervantes A, Prudkin L, Andreu J, Rodríguez-Braun E, Domingo A, Guijarro J, Gamez C, Rodon J, Di Cosimo S, Brown H, Clark J, Hardwick JS, Beckman RA, Hanley WD, Hsu K, Calvo E, Roselló S, Langdon RB, Baselga J
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2011 Oct 01; Vol. 17 (19), pp. 6304-12. Date of Electronic Publication: 2011 Aug 02.
Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: A phase I pharmacokinetic and pharmacodynamic study of dalotuzumab (MK-0646), an anti-insulin-like growth factor-1 receptor monoclonal antibody, in patients with advanced solid tumors.
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  Data: <searchLink fieldCode="AU" term="%22Atzori+F%22">Atzori F</searchLink>; Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Tabernero+J%22">Tabernero J</searchLink><br /><searchLink fieldCode="AU" term="%22Cervantes+A%22">Cervantes A</searchLink><br /><searchLink fieldCode="AU" term="%22Prudkin+L%22">Prudkin L</searchLink><br /><searchLink fieldCode="AU" term="%22Andreu+J%22">Andreu J</searchLink><br /><searchLink fieldCode="AU" term="%22Rodríguez-Braun+E%22">Rodríguez-Braun E</searchLink><br /><searchLink fieldCode="AU" term="%22Domingo+A%22">Domingo A</searchLink><br /><searchLink fieldCode="AU" term="%22Guijarro+J%22">Guijarro J</searchLink><br /><searchLink fieldCode="AU" term="%22Gamez+C%22">Gamez C</searchLink><br /><searchLink fieldCode="AU" term="%22Rodon+J%22">Rodon J</searchLink><br /><searchLink fieldCode="AU" term="%22Di+Cosimo+S%22">Di Cosimo S</searchLink><br /><searchLink fieldCode="AU" term="%22Brown+H%22">Brown H</searchLink><br /><searchLink fieldCode="AU" term="%22Clark+J%22">Clark J</searchLink><br /><searchLink fieldCode="AU" term="%22Hardwick+JS%22">Hardwick JS</searchLink><br /><searchLink fieldCode="AU" term="%22Beckman+RA%22">Beckman RA</searchLink><br /><searchLink fieldCode="AU" term="%22Hanley+WD%22">Hanley WD</searchLink><br /><searchLink fieldCode="AU" term="%22Hsu+K%22">Hsu K</searchLink><br /><searchLink fieldCode="AU" term="%22Calvo+E%22">Calvo E</searchLink><br /><searchLink fieldCode="AU" term="%22Roselló+S%22">Roselló S</searchLink><br /><searchLink fieldCode="AU" term="%22Langdon+RB%22">Langdon RB</searchLink><br /><searchLink fieldCode="AU" term="%22Baselga+J%22">Baselga J</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2011 Oct 01; Vol. 17 (19), pp. 6304-12. <i>Date of Electronic Publication: </i>2011 Aug 02.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502500 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-3265 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210780432%22">10780432 </searchLink><i>NLM ISO Abbreviation: </i>Clin Cancer Res <i>Subsets: </i>MEDLINE
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              Text: 2011 Oct 01
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