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VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC.

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Title: VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC.
Authors: Lu H; Tumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, Washington, USA., Dietsch GN, Matthews MA, Yang Y, Ghanekar S, Inokuma M, Suni M, Maino VC, Henderson KE, Howbert JJ, Disis ML, Hershberg RM
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2012 Jan 15; Vol. 18 (2), pp. 499-509. Date of Electronic Publication: 2011 Nov 29.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 22128302
AccessLevel: 2
PubType: Academic Journal
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  Data: VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC.
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  Data: <searchLink fieldCode="AU" term="%22Lu+H%22">Lu H</searchLink>; Tumor Vaccine Group, Center for Translational Medicine in Women's Health, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Dietsch+GN%22">Dietsch GN</searchLink><br /><searchLink fieldCode="AU" term="%22Matthews+MA%22">Matthews MA</searchLink><br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink><br /><searchLink fieldCode="AU" term="%22Ghanekar+S%22">Ghanekar S</searchLink><br /><searchLink fieldCode="AU" term="%22Inokuma+M%22">Inokuma M</searchLink><br /><searchLink fieldCode="AU" term="%22Suni+M%22">Suni M</searchLink><br /><searchLink fieldCode="AU" term="%22Maino+VC%22">Maino VC</searchLink><br /><searchLink fieldCode="AU" term="%22Henderson+KE%22">Henderson KE</searchLink><br /><searchLink fieldCode="AU" term="%22Howbert+JJ%22">Howbert JJ</searchLink><br /><searchLink fieldCode="AU" term="%22Disis+ML%22">Disis ML</searchLink><br /><searchLink fieldCode="AU" term="%22Hershberg+RM%22">Hershberg RM</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2012 Jan 15; Vol. 18 (2), pp. 499-509. <i>Date of Electronic Publication: </i>2011 Nov 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502500 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-3265 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210780432%22">10780432 </searchLink><i>NLM ISO Abbreviation: </i>Clin Cancer Res <i>Subsets: </i>MEDLINE
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      – Type: doi
        Value: 10.1158/1078-0432.CCR-11-1625
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      – Code: eng
        Text: English
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              Text: 2012 Jan 15
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