ABT-737 synergizes with bortezomib to induce apoptosis, mediated by Bid cleavage, Bax activation, and mitochondrial dysfunction in an Akt-dependent context in malignant human glioma cell lines.
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| Title: | ABT-737 synergizes with bortezomib to induce apoptosis, mediated by Bid cleavage, Bax activation, and mitochondrial dysfunction in an Akt-dependent context in malignant human glioma cell lines. |
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| Authors: | Premkumar DR; Department of Neurosurgery, Children's Hospital of Pittsburgh, 4401 Penn Avenue, Pittsburgh, PA 15224, USA., Jane EP, DiDomenico JD, Vukmer NA, Agostino NR, Pollack IF |
| Source: | The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2012 Jun; Vol. 341 (3), pp. 859-72. Date of Electronic Publication: 2012 Mar 05. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0376362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0103 (Electronic) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 22393246 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: ABT-737 synergizes with bortezomib to induce apoptosis, mediated by Bid cleavage, Bax activation, and mitochondrial dysfunction in an Akt-dependent context in malignant human glioma cell lines. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Premkumar+DR%22">Premkumar DR</searchLink>; Department of Neurosurgery, Children's Hospital of Pittsburgh, 4401 Penn Avenue, Pittsburgh, PA 15224, USA.<br /><searchLink fieldCode="AU" term="%22Jane+EP%22">Jane EP</searchLink><br /><searchLink fieldCode="AU" term="%22DiDomenico+JD%22">DiDomenico JD</searchLink><br /><searchLink fieldCode="AU" term="%22Vukmer+NA%22">Vukmer NA</searchLink><br /><searchLink fieldCode="AU" term="%22Agostino+NR%22">Agostino NR</searchLink><br /><searchLink fieldCode="AU" term="%22Pollack+IF%22">Pollack IF</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220376362%22">The Journal of pharmacology and experimental therapeutics</searchLink> [J Pharmacol Exp Ther] 2012 Jun; Vol. 341 (3), pp. 859-72. <i>Date of Electronic Publication: </i>2012 Mar 05. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>0376362 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1521-0103 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200223565%22">00223565 </searchLink><i>NLM ISO Abbreviation: </i>J Pharmacol Exp Ther <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=22393246 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1124/jpet.112.191536 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 859 Titles: – TitleFull: ABT-737 synergizes with bortezomib to induce apoptosis, mediated by Bid cleavage, Bax activation, and mitochondrial dysfunction in an Akt-dependent context in malignant human glioma cell lines. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Premkumar DR – PersonEntity: Name: NameFull: Jane EP – PersonEntity: Name: NameFull: DiDomenico JD – PersonEntity: Name: NameFull: Vukmer NA – PersonEntity: Name: NameFull: Agostino NR – PersonEntity: Name: NameFull: Pollack IF IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: 2012 Jun Type: published Y: 2012 Identifiers: – Type: issn-electronic Value: 1521-0103 Numbering: – Type: volume Value: 341 – Type: issue Value: 3 Titles: – TitleFull: The Journal of pharmacology and experimental therapeutics Type: main |
| ResultId | 1 |