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Design and synthesis of dihydrobenzofuran amides as orally bioavailable, centrally active γ-secretase modulators.

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Title: Design and synthesis of dihydrobenzofuran amides as orally bioavailable, centrally active γ-secretase modulators.
Authors: Pettersson M; Neuroscience Medicinal Chemistry, Pfizer Worldwide Research and Development, Groton, CT 06340, USA. martin.pettersson@pfizer.com, Johnson DS, Subramanyam C, Bales KR, am Ende CW, Fish BA, Green ME, Kauffman GW, Lira R, Mullins PB, Navaratnam T, Sakya SM, Stiff CM, Tran TP, Vetelino BC, Xie L, Zhang L, Pustilnik LR, Wood KM, O'Donnell CJ
Source: Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2012 Apr 15; Vol. 22 (8), pp. 2906-11. Date of Electronic Publication: 2012 Mar 01.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Design and synthesis of dihydrobenzofuran amides as orally bioavailable, centrally active γ-secretase modulators.
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  Data: <searchLink fieldCode="AU" term="%22Pettersson+M%22">Pettersson M</searchLink>; Neuroscience Medicinal Chemistry, Pfizer Worldwide Research and Development, Groton, CT 06340, USA. martin.pettersson@pfizer.com<br /><searchLink fieldCode="AU" term="%22Johnson+DS%22">Johnson DS</searchLink><br /><searchLink fieldCode="AU" term="%22Subramanyam+C%22">Subramanyam C</searchLink><br /><searchLink fieldCode="AU" term="%22Bales+KR%22">Bales KR</searchLink><br /><searchLink fieldCode="AU" term="%22am+Ende+CW%22">am Ende CW</searchLink><br /><searchLink fieldCode="AU" term="%22Fish+BA%22">Fish BA</searchLink><br /><searchLink fieldCode="AU" term="%22Green+ME%22">Green ME</searchLink><br /><searchLink fieldCode="AU" term="%22Kauffman+GW%22">Kauffman GW</searchLink><br /><searchLink fieldCode="AU" term="%22Lira+R%22">Lira R</searchLink><br /><searchLink fieldCode="AU" term="%22Mullins+PB%22">Mullins PB</searchLink><br /><searchLink fieldCode="AU" term="%22Navaratnam+T%22">Navaratnam T</searchLink><br /><searchLink fieldCode="AU" term="%22Sakya+SM%22">Sakya SM</searchLink><br /><searchLink fieldCode="AU" term="%22Stiff+CM%22">Stiff CM</searchLink><br /><searchLink fieldCode="AU" term="%22Tran+TP%22">Tran TP</searchLink><br /><searchLink fieldCode="AU" term="%22Vetelino+BC%22">Vetelino BC</searchLink><br /><searchLink fieldCode="AU" term="%22Xie+L%22">Xie L</searchLink><br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink><br /><searchLink fieldCode="AU" term="%22Pustilnik+LR%22">Pustilnik LR</searchLink><br /><searchLink fieldCode="AU" term="%22Wood+KM%22">Wood KM</searchLink><br /><searchLink fieldCode="AU" term="%22O'Donnell+CJ%22">O'Donnell CJ</searchLink>
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  Data: <searchLink fieldCode="JN" term="%229107377%22">Bioorganic & medicinal chemistry letters</searchLink> [Bioorg Med Chem Lett] 2012 Apr 15; Vol. 22 (8), pp. 2906-11. <i>Date of Electronic Publication: </i>2012 Mar 01.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ltd%22">Elsevier Science Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9107377 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1464-3405 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220960894X%22">0960894X </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Med Chem Lett <i>Subsets: </i>MEDLINE
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