A novel regulatory pathway for autoimmune disease: binding of partial MHC class II constructs to monocytes reduces CD74 expression and induces both specific and bystander T-cell tolerance.
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| Title: | A novel regulatory pathway for autoimmune disease: binding of partial MHC class II constructs to monocytes reduces CD74 expression and induces both specific and bystander T-cell tolerance. |
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| Authors: | Vandenbark AA; Research Service, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA.; Neuroimmunology Research, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA.; Tykeson MS Research Laboratory, UHS-46, 3181 SW Sam Jackson Park Rd, Oregon Health & Science University, Portland, OR 97239, USA.; Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA.; Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, OR 97239, USA., Meza-Romero R; Neuroimmunology Research, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA.; Tykeson MS Research Laboratory, UHS-46, 3181 SW Sam Jackson Park Rd, Oregon Health & Science University, Portland, OR 97239, USA., Benedek G; Neuroimmunology Research, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA.; Tykeson MS Research Laboratory, UHS-46, 3181 SW Sam Jackson Park Rd, Oregon Health & Science University, Portland, OR 97239, USA.; Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA., Andrew S; Neuroimmunology Research, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA.; Tykeson MS Research Laboratory, UHS-46, 3181 SW Sam Jackson Park Rd, Oregon Health & Science University, Portland, OR 97239, USA., Huan J; Tykeson MS Research Laboratory, UHS-46, 3181 SW Sam Jackson Park Rd, Oregon Health & Science University, Portland, OR 97239, USA., Chou YK; Tykeson MS Research Laboratory, UHS-46, 3181 SW Sam Jackson Park Rd, Oregon Health & Science University, Portland, OR 97239, USA.; Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA., Buenafe AC; Tykeson MS Research Laboratory, UHS-46, 3181 SW Sam Jackson Park Rd, Oregon Health & Science University, Portland, OR 97239, USA., Dahan R; Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel., Reiter Y; Faculty of Biology, Technion-Israel Institute of Technology, Haifa, Israel., Mooney JL; Tykeson MS Research Laboratory, UHS-46, 3181 SW Sam Jackson Park Rd, Oregon Health & Science University, Portland, OR 97239, USA., Offner H; Neuroimmunology Research, Department of Veterans Affairs Medical Center, Portland, OR 97239, USA.; Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA.; Department of Anesthesiology and Perioperative Medicine, Oregon Health & Science University, Portland, OR 97239, USA., Burrows GG; Tykeson MS Research Laboratory, UHS-46, 3181 SW Sam Jackson Park Rd, Oregon Health & Science University, Portland, OR 97239, USA.; Department of Neurology, Oregon Health & Science University, Portland, OR 97239, USA.; Department of Biochemistry, Oregon Health & Science University, Portland, OR 97239, USA.; Hematology & Medical Oncology, Knight Cancer Institute, Oregon Health & Science University, Portland, OR 97239, USA. |
| Source: | Journal of autoimmunity [J Autoimmun] 2013 Feb; Vol. 40, pp. 96-110. Date of Electronic Publication: 2012 Sep 29. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Academic Press Country of Publication: England NLM ID: 8812164 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9157 (Electronic) Linking ISSN: 08968411 NLM ISO Abbreviation: J Autoimmun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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