Development of macrocyclic inhibitors of HCV NS3/4A protease with cyclic constrained P2-P4 linkers. - Rudd MT; McIntyre CJ; Romano JJ; Butcher JW; Holloway MK; Bush K; Nguyen KT; Gilbert KF; Lyle TA; Liverton NJ; Wan BL; Summa V; et al. (Bioorganic & medicinal chemistry letters, 2012)