Mutagenesis of a specificity-determining residue in tyrosine hydroxylase establishes that the enzyme is a robust phenylalanine hydroxylase but a fragile tyrosine hydroxylase.

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Title: Mutagenesis of a specificity-determining residue in tyrosine hydroxylase establishes that the enzyme is a robust phenylalanine hydroxylase but a fragile tyrosine hydroxylase.
Authors: Daubner SC; Department of Biological Sciences, St. Mary's University, San Antonio, Texas 78228, United States. sdaubner@stmarytx.edu, Avila A, Bailey JO, Barrera D, Bermudez JY, Giles DH, Khan CA, Shaheen N, Thompson JW, Vasquez J, Oxley SP, Fitzpatrick PF
Source: Biochemistry [Biochemistry] 2013 Feb 26; Vol. 52 (8), pp. 1446-55. Date of Electronic Publication: 2013 Feb 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mutagenesis of a specificity-determining residue in tyrosine hydroxylase establishes that the enzyme is a robust phenylalanine hydroxylase but a fragile tyrosine hydroxylase.
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  Data: <searchLink fieldCode="AU" term="%22Daubner+SC%22">Daubner SC</searchLink>; Department of Biological Sciences, St. Mary's University, San Antonio, Texas 78228, United States. sdaubner@stmarytx.edu<br /><searchLink fieldCode="AU" term="%22Avila+A%22">Avila A</searchLink><br /><searchLink fieldCode="AU" term="%22Bailey+JO%22">Bailey JO</searchLink><br /><searchLink fieldCode="AU" term="%22Barrera+D%22">Barrera D</searchLink><br /><searchLink fieldCode="AU" term="%22Bermudez+JY%22">Bermudez JY</searchLink><br /><searchLink fieldCode="AU" term="%22Giles+DH%22">Giles DH</searchLink><br /><searchLink fieldCode="AU" term="%22Khan+CA%22">Khan CA</searchLink><br /><searchLink fieldCode="AU" term="%22Shaheen+N%22">Shaheen N</searchLink><br /><searchLink fieldCode="AU" term="%22Thompson+JW%22">Thompson JW</searchLink><br /><searchLink fieldCode="AU" term="%22Vasquez+J%22">Vasquez J</searchLink><br /><searchLink fieldCode="AU" term="%22Oxley+SP%22">Oxley SP</searchLink><br /><searchLink fieldCode="AU" term="%22Fitzpatrick+PF%22">Fitzpatrick PF</searchLink>
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  Data: <searchLink fieldCode="JN" term="%220370623%22">Biochemistry</searchLink> [Biochemistry] 2013 Feb 26; Vol. 52 (8), pp. 1446-55. <i>Date of Electronic Publication: </i>2013 Feb 13.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0370623 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4995 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200062960%22">00062960 </searchLink><i>NLM ISO Abbreviation: </i>Biochemistry <i>Subsets: </i>MEDLINE
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        Value: 10.1021/bi400031n
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        Text: English
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      – TitleFull: Mutagenesis of a specificity-determining residue in tyrosine hydroxylase establishes that the enzyme is a robust phenylalanine hydroxylase but a fragile tyrosine hydroxylase.
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              Text: 2013 Feb 26
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