An investigation of CYP2D6 genotype and response to metoprolol CR/XL during dose titration in patients with heart failure: a MERIT-HF substudy.

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Title: An investigation of CYP2D6 genotype and response to metoprolol CR/XL during dose titration in patients with heart failure: a MERIT-HF substudy.
Authors: Batty JA; School of Medicine, University of Leeds, Leeds, UK., Hall AS; Division of Epidemiology, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, UK., White HL; Division of Epidemiology, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, UK., Wikstrand J; Wallenberg Laboratory for Cardiovascular Research, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden., de Boer RA; Department of Cardiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands., van Veldhuisen DJ; Department of Cardiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands., van der Harst P; Department of Cardiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands., Waagstein F; Wallenberg Laboratory for Cardiovascular Research, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden., Hjalmarson Å; Wallenberg Laboratory for Cardiovascular Research, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden., Kjekshus J; Department of Cardiology, Rikshospitalet, University of Oslo, Oslo, Norway., Balmforth AJ; Division of Epidemiology, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, UK.
Corporate Authors: MERIT-HF Study Group
Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2014 Mar; Vol. 95 (3), pp. 321-30. Date of Electronic Publication: 2013 Sep 30.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1532-6535
DOI:10.1038/clpt.2013.193