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Repurposing diflunisal for familial amyloid polyneuropathy: a randomized clinical trial.

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Title: Repurposing diflunisal for familial amyloid polyneuropathy: a randomized clinical trial.
Authors: Berk JL; Amyloidosis Center, Departments of Medicine and Neurology, Boston University School of Medicine, Boston, Massachusetts., Suhr OB; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Obici L; Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo and Department of Molecular Medicine, University of Pavia, Pavia, Italy., Sekijima Y; Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan., Zeldenrust SR; Departments of Medicine and Neurology, Mayo Clinic, Rochester, Minnesota., Yamashita T; Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Heneghan MA; Institute of Liver Studies, King's College Hospital Foundation Trust, London, England., Gorevic PD; Departments of Medicine and Neurology, Mount Sinai School of Medicine, New York, New York., Litchy WJ; Departments of Medicine and Neurology, Mayo Clinic, Rochester, Minnesota., Wiesman JF; Amyloidosis Center, Departments of Medicine and Neurology, Boston University School of Medicine, Boston, Massachusetts., Nordh E; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden., Corato M; Istituto Clinico Humanitas, Rozzano, Italy., Lozza A; C. Mondino National Institute of Neurology, Foundation IRCCS, Pavia, Italy., Cortese A; C. Mondino National Institute of Neurology, Foundation IRCCS, Pavia, Italy., Robinson-Papp J; Departments of Medicine and Neurology, Mount Sinai School of Medicine, New York, New York., Colton T; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts., Rybin DV; Data Coordinating Center, Boston University School of Public Health, Boston, Massachusetts., Bisbee AB; Data Coordinating Center, Boston University School of Public Health, Boston, Massachusetts., Ando Y; Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan., Ikeda S; Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan., Seldin DC; Amyloidosis Center, Departments of Medicine and Neurology, Boston University School of Medicine, Boston, Massachusetts., Merlini G; Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo and Department of Molecular Medicine, University of Pavia, Pavia, Italy., Skinner M; Amyloidosis Center, Departments of Medicine and Neurology, Boston University School of Medicine, Boston, Massachusetts., Kelly JW; Departments of Chemistry and Molecular and Experimental Medicine and Skaggs Institute of Chemical Biology, Scripps Research Institute, La Jolla, California., Dyck PJ; Departments of Medicine and Neurology, Mayo Clinic, Rochester, Minnesota.
Corporate Authors: Diflunisal Trial Consortium
Source: JAMA [JAMA] 2013 Dec 25; Vol. 310 (24), pp. 2658-67.
Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 7501160 Publication Model: Print Cited Medium: Internet ISSN: 1538-3598 (Electronic) Linking ISSN: 00987484 NLM ISO Abbreviation: JAMA Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Berk+JL%22">Berk JL</searchLink>; Amyloidosis Center, Departments of Medicine and Neurology, Boston University School of Medicine, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Suhr+OB%22">Suhr OB</searchLink>; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.<br /><searchLink fieldCode="AU" term="%22Obici+L%22">Obici L</searchLink>; Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo and Department of Molecular Medicine, University of Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Sekijima+Y%22">Sekijima Y</searchLink>; Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan.<br /><searchLink fieldCode="AU" term="%22Zeldenrust+SR%22">Zeldenrust SR</searchLink>; Departments of Medicine and Neurology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Yamashita+T%22">Yamashita T</searchLink>; Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Heneghan+MA%22">Heneghan MA</searchLink>; Institute of Liver Studies, King's College Hospital Foundation Trust, London, England.<br /><searchLink fieldCode="AU" term="%22Gorevic+PD%22">Gorevic PD</searchLink>; Departments of Medicine and Neurology, Mount Sinai School of Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Litchy+WJ%22">Litchy WJ</searchLink>; Departments of Medicine and Neurology, Mayo Clinic, Rochester, Minnesota.<br /><searchLink fieldCode="AU" term="%22Wiesman+JF%22">Wiesman JF</searchLink>; Amyloidosis Center, Departments of Medicine and Neurology, Boston University School of Medicine, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Nordh+E%22">Nordh E</searchLink>; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.<br /><searchLink fieldCode="AU" term="%22Corato+M%22">Corato M</searchLink>; Istituto Clinico Humanitas, Rozzano, Italy.<br /><searchLink fieldCode="AU" term="%22Lozza+A%22">Lozza A</searchLink>; C. Mondino National Institute of Neurology, Foundation IRCCS, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Cortese+A%22">Cortese A</searchLink>; C. Mondino National Institute of Neurology, Foundation IRCCS, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Robinson-Papp+J%22">Robinson-Papp J</searchLink>; Departments of Medicine and Neurology, Mount Sinai School of Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Colton+T%22">Colton T</searchLink>; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Rybin+DV%22">Rybin DV</searchLink>; Data Coordinating Center, Boston University School of Public Health, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Bisbee+AB%22">Bisbee AB</searchLink>; Data Coordinating Center, Boston University School of Public Health, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Ando+Y%22">Ando Y</searchLink>; Department of Neurology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.<br /><searchLink fieldCode="AU" term="%22Ikeda+S%22">Ikeda S</searchLink>; Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan.<br /><searchLink fieldCode="AU" term="%22Seldin+DC%22">Seldin DC</searchLink>; Amyloidosis Center, Departments of Medicine and Neurology, Boston University School of Medicine, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Merlini+G%22">Merlini G</searchLink>; Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo and Department of Molecular Medicine, University of Pavia, Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Skinner+M%22">Skinner M</searchLink>; Amyloidosis Center, Departments of Medicine and Neurology, Boston University School of Medicine, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Kelly+JW%22">Kelly JW</searchLink>; Departments of Chemistry and Molecular and Experimental Medicine and Skaggs Institute of Chemical Biology, Scripps Research Institute, La Jolla, California.<br /><searchLink fieldCode="AU" term="%22Dyck+PJ%22">Dyck PJ</searchLink>; Departments of Medicine and Neurology, Mayo Clinic, Rochester, Minnesota.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Medical+Association%22">American Medical Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7501160 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-3598 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200987484%22">00987484 </searchLink><i>NLM ISO Abbreviation: </i>JAMA <i>Subsets: </i>MEDLINE
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