Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells.

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Title: Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells.
Authors: Szarc vel Szic K; Laboratory of Protein Chemistry, Proteomics and Epigenetic Signaling (PPES), Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Op de Beeck K; Center of Medical Genetics, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium ; Center for Oncological Research (CORE), Laboratory of Cancer Research and Clinical Oncology, Department of Oncology, University of Antwerp, Antwerp, Belgium., Ratman D; Nuclear Receptor Signaling Unit, Cytokine Receptor Laboratory, VIB Department of Medical Protein Research, Ghent University, Ghent, Belgium., Wouters A; Center for Oncological Research (CORE), Laboratory of Cancer Research and Clinical Oncology, Department of Oncology, University of Antwerp, Antwerp, Belgium., Beck IM; Laboratory of Experimental Cancer Research (LECR), Department of Radiation Therapy and Experimental Cancer Research, Ghent University, Ghent, Belgium., Declerck K; Laboratory of Protein Chemistry, Proteomics and Epigenetic Signaling (PPES), Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Heyninck K; Laboratory of Eukaryotic Gene Expression and Signal Transduction (LEGEST), Ghent University, Ghent, Belgium., Fransen E; Center of Medical Genetics, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium ; StatUa Center for Statistics, University of Antwerp, Antwerp, Belgium., Bracke M; Laboratory of Experimental Cancer Research (LECR), Department of Radiation Therapy and Experimental Cancer Research, Ghent University, Ghent, Belgium., De Bosscher K; Nuclear Receptor Signaling Unit, Cytokine Receptor Laboratory, VIB Department of Medical Protein Research, Ghent University, Ghent, Belgium., Lardon F; Center for Oncological Research (CORE), Laboratory of Cancer Research and Clinical Oncology, Department of Oncology, University of Antwerp, Antwerp, Belgium., Van Camp G; Center of Medical Genetics, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium., Vanden Berghe W; Laboratory of Protein Chemistry, Proteomics and Epigenetic Signaling (PPES), Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
Source: PloS one [PLoS One] 2014 Feb 03; Vol. 9 (2), pp. e87850. Date of Electronic Publication: 2014 Feb 03 (Print Publication: 2014).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pharmacological levels of Withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells.
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  Data: <searchLink fieldCode="AU" term="%22Szarc+vel+Szic+K%22">Szarc vel Szic K</searchLink>; Laboratory of Protein Chemistry, Proteomics and Epigenetic Signaling (PPES), Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Op+de+Beeck+K%22">Op de Beeck K</searchLink>; Center of Medical Genetics, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium ; Center for Oncological Research (CORE), Laboratory of Cancer Research and Clinical Oncology, Department of Oncology, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Ratman+D%22">Ratman D</searchLink>; Nuclear Receptor Signaling Unit, Cytokine Receptor Laboratory, VIB Department of Medical Protein Research, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Wouters+A%22">Wouters A</searchLink>; Center for Oncological Research (CORE), Laboratory of Cancer Research and Clinical Oncology, Department of Oncology, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Beck+IM%22">Beck IM</searchLink>; Laboratory of Experimental Cancer Research (LECR), Department of Radiation Therapy and Experimental Cancer Research, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Declerck+K%22">Declerck K</searchLink>; Laboratory of Protein Chemistry, Proteomics and Epigenetic Signaling (PPES), Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Heyninck+K%22">Heyninck K</searchLink>; Laboratory of Eukaryotic Gene Expression and Signal Transduction (LEGEST), Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Fransen+E%22">Fransen E</searchLink>; Center of Medical Genetics, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium ; StatUa Center for Statistics, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Bracke+M%22">Bracke M</searchLink>; Laboratory of Experimental Cancer Research (LECR), Department of Radiation Therapy and Experimental Cancer Research, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Bosscher+K%22">De Bosscher K</searchLink>; Nuclear Receptor Signaling Unit, Cytokine Receptor Laboratory, VIB Department of Medical Protein Research, Ghent University, Ghent, Belgium.<br /><searchLink fieldCode="AU" term="%22Lardon+F%22">Lardon F</searchLink>; Center for Oncological Research (CORE), Laboratory of Cancer Research and Clinical Oncology, Department of Oncology, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Camp+G%22">Van Camp G</searchLink>; Center of Medical Genetics, Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Vanden+Berghe+W%22">Vanden Berghe W</searchLink>; Laboratory of Protein Chemistry, Proteomics and Epigenetic Signaling (PPES), Department of Biomedical Sciences, University of Antwerp, Antwerp, Belgium.
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