The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infection. - Filone CM; Caballero IS; Dower K; Mendillo ML; Cowley GS; Santagata S; Rozelle DK; Yen J; Rubins KH; Hacohen N; Root DE; Hensley LE; et al. (PLoS pathogens, 2014)