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Loss-of-function mutations in SLC30A8 protect against type 2 diabetes.

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Title: Loss-of-function mutations in SLC30A8 protect against type 2 diabetes.
Authors: Flannick J; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA., Thorleifsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Beer NL; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Jacobs SB; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Burtt NP; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Fuchsberger C; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Atzmon G; 1] Department of Medicine, Albert Einstein College of Medicine, Bronx, New York, USA. [2] Department of Genetics, Albert Einstein College of Medicine, Bronx, New York, USA., Benediktsson R; Department of Endocrinology and Metabolism, Landspitali University Hospital, Reykjavik, Iceland., Blangero J; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA., Bowden DW; 1] Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA. [2] Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA. [3] Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA. [4] Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Brandslund I; 1] Department of Clinical Biochemistry, Vejle Hospital, Vejle, Denmark. [2] Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Brosnan J; Cardiovascular & Metabolic Diseases Research Unit, Pfizer, Inc., Cambridge, Massachusetts, USA., Burslem F; Cardiovascular and Metabolic Diseases Practice, Prescient Life Sciences, London, UK., Chambers J; 1] Department of Epidemiology and Biostatistics, Imperial College London, London, UK. [2] Imperial College Healthcare National Health Service (NHS) Trust, London, UK. [3] Ealing Hospital NHS Trust, Middlesex, UK., Cho YS; Department of Biomedical Science, Hallym University, Chuncheon, Korea., Christensen C; Department of Internal Medicine and Endocrinology, Vejle Hospital, Vejle, Denmark., Douglas DA; Unit of Diabetes and Celiac Diseases, Department of Clinical Sciences, Lund University, Malmö, Sweden., Duggirala R; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA., Dymek Z; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Farjoun Y; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Fennell T; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Fontanillas P; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Forsén T; 1] Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland. [2] Diabetes Care Unit, Vaasa Health Care Centre, Vaasa, Finland., Gabriel S; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Glaser B; 1] Endocrinology and Metabolism Service, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. [2] Israel Diabetes Research Group (IDRG), Holon, Israel., Gudbjartsson DF; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Hanis C; Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA., Hansen T; 1] Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. [2] Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark., Hreidarsson AB; Department of Endocrinology and Metabolism, Landspitali University Hospital, Reykjavik, Iceland., Hveem K; Department of Public Health, Faculty of Medicine, Norwegian University of Science and Technology, Levanger, Norway., Ingelsson E; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Isomaa B; 1] Folkhalsan Research Centre, Helsinki, Finland. [2] Department of Social Services and Health Care, Jakobstad, Finland., Johansson S; 1] KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway. [2] Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway. [3] Department of Biomedicine, University of Bergen, Bergen, Norway., Jørgensen T; 1] Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark. [2] Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. [3] Faculty of Medicine, University of Aalborg, Aalborg, Denmark., Jørgensen ME; Steno Diabetes Center, Gentofte, Denmark., Kathiresan S; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Cardiovascular Research Center, Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, USA. [4] Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Kong A; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Kooner J; 1] Imperial College Healthcare National Health Service (NHS) Trust, London, UK. [2] Ealing Hospital NHS Trust, Middlesex, UK. [3] National Heart and Lung Institute (NHLI), Imperial College London, Hammersmith Hospital, London, UK., Kravic J; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden., Laakso M; Department of Medicine, University of Eastern Finland, Kuopio Campus and Kuopio University Hospital, Kuopio, Finland., Lee JY; Center for Genome Science, Korea National Institute of Health, Osong Health Technology, Chungcheongbuk-do, Korea., Lind L; Department of Medical Sciences, Uppsala University, Uppsala, Sweden., Lindgren CM; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Linneberg A; 1] Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark. [2] Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. [3] Department of Clinical Experimental Research, Glostrup University Hospital, Glostrup, Denmark., Masson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Meitinger T; Institute of Human Genetics, Technical University Munich, Munich, Germany., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA., Molven A; 1] KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway. [2] Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, Bergen, Norway. [3] Department of Pathology, Haukeland University Hospital, Bergen, Norway., Morris AP; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Department of Biostatistics, University of Liverpool, Liverpool, UK., Potluri S; Applied Quantitative Genotherapeutics, Pfizer, Inc., South San Francisco, California, USA., Rauramaa R; 1] Kuopio Research Institute of Exercise Medicine, Kuopio, Finland. [2] Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Ribel-Madsen R; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Richard AM; Cardiovascular & Metabolic Diseases Research Unit, Pfizer, Inc., Cambridge, Massachusetts, USA., Rolph T; Cardiovascular & Metabolic Diseases Research Unit, Pfizer, Inc., Cambridge, Massachusetts, USA., Salomaa V; National Institute for Health and Welfare (THL), Helsinki, Finland., Segrè AV; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA., Skärstrand H; Unit of Diabetes and Celiac Diseases, Department of Clinical Sciences, Lund University, Malmö, Sweden., Steinthorsdottir V; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Stringham HM; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Sulem P; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Tai ES; 1] Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore. [2] Department of Medicine, National University of Singapore, National University Health System, Singapore. [3] Duke-National University of Singapore Graduate Medical School, Singapore., Teo YY; 1] Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore. [2] Centre for Molecular Epidemiology, National University of Singapore, Singapore. [3] Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore. [4] Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore. [5] Department of Statistics and Applied Probability, National University of Singapore, Singapore., Teslovich T; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Thorsteinsdottir U; 1] deCODE Genetics/Amgen, Inc., Reykjavik, Iceland. [2] Faculty of Medicine, University of Iceland, Reykjavík, Iceland., Trimmer JK; Cardiovascular & Metabolic Diseases Research Unit, Pfizer, Inc., Cambridge, Massachusetts, USA., Tuomi T; 1] Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland. [2] Folkhalsan Research Centre, Helsinki, Finland., Tuomilehto J; 1] Centre for Vascular Prevention, Danube-University Krems, Krems, Austria. [2] Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland. [3] Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Vaziri-Sani F; Unit of Diabetes and Celiac Diseases, Department of Clinical Sciences, Lund University, Malmö, Sweden., Voight BF; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Department of Pharmacology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA. [3] Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi, USA., Boehnke M; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., McCarthy MI; 1] Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK. [2] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [3] Oxford National Institute for Health Research (NIHR) Biomedical Research Centre, Churchill Hospital, Oxford, UK., Njølstad PR; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway. [3] Department of Pediatrics, Haukeland University Hospital, Bergen, Norway., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Groop L; 1] Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden. [2] Finnish Institute for Molecular Medicine (FIMM), Helsinki University, Helsinki, Finland., Cox DR; Applied Quantitative Genotherapeutics, Pfizer, Inc., South San Francisco, California, USA., Stefansson K; 1] deCODE Genetics/Amgen, Inc., Reykjavik, Iceland. [2] Faculty of Medicine, University of Iceland, Reykjavík, Iceland., Altshuler D; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA. [4] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [5] Cardiovascular Research Center, Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, USA. [6] Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA. [7] Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Corporate Authors: Go-T2D Consortium, T2D-GENES Consortium
Source: Nature genetics [Nat Genet] 2014 Apr; Vol. 46 (4), pp. 357-63. Date of Electronic Publication: 2014 Mar 02.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Loss-of-function mutations in SLC30A8 protect against type 2 diabetes.
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Flannick+J%22">Flannick J</searchLink>; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Thorleifsson+G%22">Thorleifsson G</searchLink>; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Beer+NL%22">Beer NL</searchLink>; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. 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[4] Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Brandslund+I%22">Brandslund I</searchLink>; 1] Department of Clinical Biochemistry, Vejle Hospital, Vejle, Denmark. [2] Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Brosnan+J%22">Brosnan J</searchLink>; Cardiovascular & Metabolic Diseases Research Unit, Pfizer, Inc., Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Burslem+F%22">Burslem F</searchLink>; Cardiovascular and Metabolic Diseases Practice, Prescient Life Sciences, London, UK.<br /><searchLink fieldCode="AU" term="%22Chambers+J%22">Chambers J</searchLink>; 1] Department of Epidemiology and Biostatistics, Imperial College London, London, UK. [2] Imperial College Healthcare National Health Service (NHS) Trust, London, UK. [3] Ealing Hospital NHS Trust, Middlesex, UK.<br /><searchLink fieldCode="AU" term="%22Cho+YS%22">Cho YS</searchLink>; Department of Biomedical Science, Hallym University, Chuncheon, Korea.<br /><searchLink fieldCode="AU" term="%22Christensen+C%22">Christensen C</searchLink>; Department of Internal Medicine and Endocrinology, Vejle Hospital, Vejle, Denmark.<br /><searchLink fieldCode="AU" term="%22Douglas+DA%22">Douglas DA</searchLink>; Unit of Diabetes and Celiac Diseases, Department of Clinical Sciences, Lund University, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Duggirala+R%22">Duggirala R</searchLink>; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Dymek+Z%22">Dymek Z</searchLink>; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Farjoun+Y%22">Farjoun Y</searchLink>; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Fennell+T%22">Fennell T</searchLink>; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Fontanillas+P%22">Fontanillas P</searchLink>; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Forsén+T%22">Forsén T</searchLink>; 1] Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland. 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[2] Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Hreidarsson+AB%22">Hreidarsson AB</searchLink>; Department of Endocrinology and Metabolism, Landspitali University Hospital, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Hveem+K%22">Hveem K</searchLink>; Department of Public Health, Faculty of Medicine, Norwegian University of Science and Technology, Levanger, Norway.<br /><searchLink fieldCode="AU" term="%22Ingelsson+E%22">Ingelsson E</searchLink>; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Molecular Epidemiology and Science for Life Laboratory, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Isomaa+B%22">Isomaa B</searchLink>; 1] Folkhalsan Research Centre, Helsinki, Finland. 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[3] Faculty of Medicine, University of Aalborg, Aalborg, Denmark.<br /><searchLink fieldCode="AU" term="%22Jørgensen+ME%22">Jørgensen ME</searchLink>; Steno Diabetes Center, Gentofte, Denmark.<br /><searchLink fieldCode="AU" term="%22Kathiresan+S%22">Kathiresan S</searchLink>; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Cardiovascular Research Center, Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, USA. [4] Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Kong+A%22">Kong A</searchLink>; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Kooner+J%22">Kooner J</searchLink>; 1] Imperial College Healthcare National Health Service (NHS) Trust, London, UK. [2] Ealing Hospital NHS Trust, Middlesex, UK. [3] National Heart and Lung Institute (NHLI), Imperial College London, Hammersmith Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Kravic+J%22">Kravic J</searchLink>; Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Laakso+M%22">Laakso M</searchLink>; Department of Medicine, University of Eastern Finland, Kuopio Campus and Kuopio University Hospital, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Lee+JY%22">Lee JY</searchLink>; Center for Genome Science, Korea National Institute of Health, Osong Health Technology, Chungcheongbuk-do, Korea.<br /><searchLink fieldCode="AU" term="%22Lind+L%22">Lind L</searchLink>; Department of Medical Sciences, Uppsala University, Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Lindgren+CM%22">Lindgren CM</searchLink>; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Linneberg+A%22">Linneberg A</searchLink>; 1] Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark. [2] Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. [3] Department of Clinical Experimental Research, Glostrup University Hospital, Glostrup, Denmark.<br /><searchLink fieldCode="AU" term="%22Masson+G%22">Masson G</searchLink>; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Meitinger+T%22">Meitinger T</searchLink>; Institute of Human Genetics, Technical University Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Mohlke+KL%22">Mohlke KL</searchLink>; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Molven+A%22">Molven A</searchLink>; 1] KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway. [2] Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, Bergen, Norway. [3] Department of Pathology, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Morris+AP%22">Morris AP</searchLink>; 1] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [2] Department of Biostatistics, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Potluri+S%22">Potluri S</searchLink>; Applied Quantitative Genotherapeutics, Pfizer, Inc., South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Rauramaa+R%22">Rauramaa R</searchLink>; 1] Kuopio Research Institute of Exercise Medicine, Kuopio, Finland. [2] Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland.<br /><searchLink fieldCode="AU" term="%22Ribel-Madsen+R%22">Ribel-Madsen R</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Richard+AM%22">Richard AM</searchLink>; Cardiovascular & Metabolic Diseases Research Unit, Pfizer, Inc., Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Rolph+T%22">Rolph T</searchLink>; Cardiovascular & Metabolic Diseases Research Unit, Pfizer, Inc., Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Salomaa+V%22">Salomaa V</searchLink>; National Institute for Health and Welfare (THL), Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Segrè+AV%22">Segrè AV</searchLink>; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Skärstrand+H%22">Skärstrand H</searchLink>; Unit of Diabetes and Celiac Diseases, Department of Clinical Sciences, Lund University, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Steinthorsdottir+V%22">Steinthorsdottir V</searchLink>; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Stringham+HM%22">Stringham HM</searchLink>; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Sulem+P%22">Sulem P</searchLink>; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Tai+ES%22">Tai ES</searchLink>; 1] Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore. [2] Department of Medicine, National University of Singapore, National University Health System, Singapore. [3] Duke-National University of Singapore Graduate Medical School, Singapore.<br /><searchLink fieldCode="AU" term="%22Teo+YY%22">Teo YY</searchLink>; 1] Saw Swee Hock School of Public Health, National University of Singapore, National University Health System, Singapore. [2] Centre for Molecular Epidemiology, National University of Singapore, Singapore. [3] Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore. [4] Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore. [5] Department of Statistics and Applied Probability, National University of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Teslovich+T%22">Teslovich T</searchLink>; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Thorsteinsdottir+U%22">Thorsteinsdottir U</searchLink>; 1] deCODE Genetics/Amgen, Inc., Reykjavik, Iceland. [2] Faculty of Medicine, University of Iceland, Reykjavík, Iceland.<br /><searchLink fieldCode="AU" term="%22Trimmer+JK%22">Trimmer JK</searchLink>; Cardiovascular & Metabolic Diseases Research Unit, Pfizer, Inc., Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Tuomi+T%22">Tuomi T</searchLink>; 1] Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland. [2] Folkhalsan Research Centre, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Tuomilehto+J%22">Tuomilehto J</searchLink>; 1] Centre for Vascular Prevention, Danube-University Krems, Krems, Austria. [2] Diabetes Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland. [3] Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Vaziri-Sani+F%22">Vaziri-Sani F</searchLink>; Unit of Diabetes and Celiac Diseases, Department of Clinical Sciences, Lund University, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Voight+BF%22">Voight BF</searchLink>; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Department of Pharmacology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA. [3] Department of Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Wilson+JG%22">Wilson JG</searchLink>; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, Mississippi, USA.<br /><searchLink fieldCode="AU" term="%22Boehnke+M%22">Boehnke M</searchLink>; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22McCarthy+MI%22">McCarthy MI</searchLink>; 1] Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK. [2] Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK. [3] Oxford National Institute for Health Research (NIHR) Biomedical Research Centre, Churchill Hospital, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Njølstad+PR%22">Njølstad PR</searchLink>; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway. [3] Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Pedersen+O%22">Pedersen O</searchLink>; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Groop+L%22">Groop L</searchLink>; 1] Department of Clinical Sciences, Diabetes and Endocrinology, Lund University Diabetes Centre, Malmö, Sweden. [2] Finnish Institute for Molecular Medicine (FIMM), Helsinki University, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Cox+DR%22">Cox DR</searchLink>; Applied Quantitative Genotherapeutics, Pfizer, Inc., South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Stefansson+K%22">Stefansson K</searchLink>; 1] deCODE Genetics/Amgen, Inc., Reykjavik, Iceland. [2] Faculty of Medicine, University of Iceland, Reykjavík, Iceland.<br /><searchLink fieldCode="AU" term="%22Altshuler+D%22">Altshuler D</searchLink>; 1] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [2] Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA. [4] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [5] Cardiovascular Research Center, Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, USA. [6] Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA. [7] Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
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  Data: <searchLink fieldCode="JN" term="%229216904%22">Nature genetics</searchLink> [Nat Genet] 2014 Apr; Vol. 46 (4), pp. 357-63. <i>Date of Electronic Publication: </i>2014 Mar 02.
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      – TitleFull: Loss-of-function mutations in SLC30A8 protect against type 2 diabetes.
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