View in EDS

The identification of novel 5'-amino gemcitabine analogs as potent RRM1 inhibitors.

Saved in:
Bibliographic Details
Title: The identification of novel 5'-amino gemcitabine analogs as potent RRM1 inhibitors.
Authors: Labroli MA; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA. Electronic address: marc.labroli@merck.com., Dwyer MP; Merck Research Laboratories, PO Box 2000, Rahway, NJ 07065, USA., Shen R; Merck Research Laboratories, 33 Avenue Louis Pasteur, BMB-3, Boston, MA 02115, USA., Popovici-Muller J; Merck Research Laboratories, 33 Avenue Louis Pasteur, BMB-3, Boston, MA 02115, USA., Pu Q; Merck Research Laboratories, 33 Avenue Louis Pasteur, BMB-3, Boston, MA 02115, USA., Wyss D; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., McCoy M; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Barrett D; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Davis N; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA., Seghezzi W; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA., Shanahan F; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA., Taricani L; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA., Beaumont M; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA., Malinao MC; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA., Parry D; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA., Guzi TJ; Merck Research Laboratories, 33 Avenue Louis Pasteur, BMB-3, Boston, MA 02115, USA.
Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2014 Apr 01; Vol. 22 (7), pp. 2303-10. Date of Electronic Publication: 2014 Feb 15.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 24588962
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: The identification of novel 5'-amino gemcitabine analogs as potent RRM1 inhibitors.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Labroli+MA%22">Labroli MA</searchLink>; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA. Electronic address: marc.labroli@merck.com.<br /><searchLink fieldCode="AU" term="%22Dwyer+MP%22">Dwyer MP</searchLink>; Merck Research Laboratories, PO Box 2000, Rahway, NJ 07065, USA.<br /><searchLink fieldCode="AU" term="%22Shen+R%22">Shen R</searchLink>; Merck Research Laboratories, 33 Avenue Louis Pasteur, BMB-3, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Popovici-Muller+J%22">Popovici-Muller J</searchLink>; Merck Research Laboratories, 33 Avenue Louis Pasteur, BMB-3, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Pu+Q%22">Pu Q</searchLink>; Merck Research Laboratories, 33 Avenue Louis Pasteur, BMB-3, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Wyss+D%22">Wyss D</searchLink>; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA.<br /><searchLink fieldCode="AU" term="%22McCoy+M%22">McCoy M</searchLink>; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA.<br /><searchLink fieldCode="AU" term="%22Barrett+D%22">Barrett D</searchLink>; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA.<br /><searchLink fieldCode="AU" term="%22Davis+N%22">Davis N</searchLink>; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Seghezzi+W%22">Seghezzi W</searchLink>; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Shanahan+F%22">Shanahan F</searchLink>; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Taricani+L%22">Taricani L</searchLink>; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Beaumont+M%22">Beaumont M</searchLink>; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Malinao+MC%22">Malinao MC</searchLink>; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Parry+D%22">Parry D</searchLink>; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA.<br /><searchLink fieldCode="AU" term="%22Guzi+TJ%22">Guzi TJ</searchLink>; Merck Research Laboratories, 33 Avenue Louis Pasteur, BMB-3, Boston, MA 02115, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%229413298%22">Bioorganic & medicinal chemistry</searchLink> [Bioorg Med Chem] 2014 Apr 01; Vol. 22 (7), pp. 2303-10. <i>Date of Electronic Publication: </i>2014 Feb 15.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science%22">Elsevier Science </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9413298 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1464-3391 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209680896%22">09680896 </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Med Chem <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=24588962
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.bmc.2014.02.007
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 2303
    Titles:
      – TitleFull: The identification of novel 5'-amino gemcitabine analogs as potent RRM1 inhibitors.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Labroli MA
      – PersonEntity:
          Name:
            NameFull: Dwyer MP
      – PersonEntity:
          Name:
            NameFull: Shen R
      – PersonEntity:
          Name:
            NameFull: Popovici-Muller J
      – PersonEntity:
          Name:
            NameFull: Pu Q
      – PersonEntity:
          Name:
            NameFull: Wyss D
      – PersonEntity:
          Name:
            NameFull: McCoy M
      – PersonEntity:
          Name:
            NameFull: Barrett D
      – PersonEntity:
          Name:
            NameFull: Davis N
      – PersonEntity:
          Name:
            NameFull: Seghezzi W
      – PersonEntity:
          Name:
            NameFull: Shanahan F
      – PersonEntity:
          Name:
            NameFull: Taricani L
      – PersonEntity:
          Name:
            NameFull: Beaumont M
      – PersonEntity:
          Name:
            NameFull: Malinao MC
      – PersonEntity:
          Name:
            NameFull: Parry D
      – PersonEntity:
          Name:
            NameFull: Guzi TJ
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 04
              Text: 2014 Apr 01
              Type: published
              Y: 2014
          Identifiers:
            – Type: issn-electronic
              Value: 1464-3391
          Numbering:
            – Type: volume
              Value: 22
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Bioorganic & medicinal chemistry
              Type: main
ResultId 1