The identification of novel 5'-amino gemcitabine analogs as potent RRM1 inhibitors.
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| Title: | The identification of novel 5'-amino gemcitabine analogs as potent RRM1 inhibitors. |
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| Authors: | Labroli MA; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA. Electronic address: marc.labroli@merck.com., Dwyer MP; Merck Research Laboratories, PO Box 2000, Rahway, NJ 07065, USA., Shen R; Merck Research Laboratories, 33 Avenue Louis Pasteur, BMB-3, Boston, MA 02115, USA., Popovici-Muller J; Merck Research Laboratories, 33 Avenue Louis Pasteur, BMB-3, Boston, MA 02115, USA., Pu Q; Merck Research Laboratories, 33 Avenue Louis Pasteur, BMB-3, Boston, MA 02115, USA., Wyss D; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., McCoy M; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Barrett D; Merck Research Laboratories, 2000 Galloping Hill Road, Kenilworth, NJ 07033, USA., Davis N; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA., Seghezzi W; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA., Shanahan F; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA., Taricani L; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA., Beaumont M; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA., Malinao MC; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA., Parry D; Merck Research Laboratories, 901 South California Avenue, Palo Alto, CA 94304, USA., Guzi TJ; Merck Research Laboratories, 33 Avenue Louis Pasteur, BMB-3, Boston, MA 02115, USA. |
| Source: | Bioorganic & medicinal chemistry [Bioorg Med Chem] 2014 Apr 01; Vol. 22 (7), pp. 2303-10. Date of Electronic Publication: 2014 Feb 15. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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