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Impact of CYP2D6 polymorphisms on clinical efficacy and tolerability of metoprolol tartrate.

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Title: Impact of CYP2D6 polymorphisms on clinical efficacy and tolerability of metoprolol tartrate.
Authors: Hamadeh IS; Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA., Langaee TY; Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA., Dwivedi R; Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA., Garcia S; Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA., Burkley BM; Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA., Skaar TC; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA., Chapman AB; Renal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA., Gums JG; 1] Department of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, Florida, USA [2] Department of Community Health and Family Medicine, University of Florida College of Medicine, Gainesville, Florida, USA., Turner ST; Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA., Gong Y; Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA., Cooper-DeHoff RM; 1] Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA [2] Division of Cardiology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA., Johnson JA; 1] Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA [2] Division of Cardiology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.
Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2014 Aug; Vol. 96 (2), pp. 175-81. Date of Electronic Publication: 2014 Mar 17.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Impact of CYP2D6 polymorphisms on clinical efficacy and tolerability of metoprolol tartrate.
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  Data: <searchLink fieldCode="AU" term="%22Hamadeh+IS%22">Hamadeh IS</searchLink>; Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Langaee+TY%22">Langaee TY</searchLink>; Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Dwivedi+R%22">Dwivedi R</searchLink>; Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Garcia+S%22">Garcia S</searchLink>; Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Burkley+BM%22">Burkley BM</searchLink>; Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Skaar+TC%22">Skaar TC</searchLink>; Division of Clinical Pharmacology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA.<br /><searchLink fieldCode="AU" term="%22Chapman+AB%22">Chapman AB</searchLink>; Renal Division, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.<br /><searchLink fieldCode="AU" term="%22Gums+JG%22">Gums JG</searchLink>; 1] Department of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, Florida, USA [2] Department of Community Health and Family Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Turner+ST%22">Turner ST</searchLink>; Division of Nephrology and Hypertension, Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Gong+Y%22">Gong Y</searchLink>; Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Cooper-DeHoff+RM%22">Cooper-DeHoff RM</searchLink>; 1] Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA [2] Division of Cardiology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+JA%22">Johnson JA</searchLink>; 1] Department of Pharmacotherapy and Translational Research, Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, Florida, USA [2] Division of Cardiology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.
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