Treatment with a histone deacetylase inhibitor, valproic acid, is associated with increased platelet activation in a large animal model of traumatic brain injury and hemorrhagic shock.

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Bibliographic Details
Title: Treatment with a histone deacetylase inhibitor, valproic acid, is associated with increased platelet activation in a large animal model of traumatic brain injury and hemorrhagic shock.
Authors: Dekker SE; Department of Surgery, University of Michigan Hospital, Ann Arbor, Michigan; Department of Anesthesiology, VU University Medical Center, Institute for Cardiovascular Research, Amsterdam, the Netherlands., Sillesen M; Division of Trauma, Emergency Surgery And Surgical Critical Care, Department of Surgery, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts; Department of Surgery, Copenhagen University Hospital, Hillerød, Denmark., Bambakidis T; Department of Surgery, University of Michigan Hospital, Ann Arbor, Michigan., Andjelkovic AV; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan; Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, Michigan., Jin G; Department of Surgery, University of Michigan Hospital, Ann Arbor, Michigan., Liu B; Department of Surgery, University of Michigan Hospital, Ann Arbor, Michigan., Boer C; Department of Anesthesiology, VU University Medical Center, Institute for Cardiovascular Research, Amsterdam, the Netherlands., Johansson PI; Capital Region Blood Bank, University of Copenhagen, Rigshospitalet, Denmark; Department of Surgery, University of Texas Medical School, Centre for Translational Injury Research (CeTIR), Houston, Texas., Linzel D; Department of Surgery, University of Michigan Hospital, Ann Arbor, Michigan; Department of Emergency Medicine, VU University Medical Center, Amsterdam, the Netherlands., Halaweish I; Department of Surgery, University of Michigan Hospital, Ann Arbor, Michigan., Alam HB; Department of Surgery, University of Michigan Hospital, Ann Arbor, Michigan. Electronic address: alamh@med.umich.edu.
Source: The Journal of surgical research [J Surg Res] 2014 Jul; Vol. 190 (1), pp. 312-8. Date of Electronic Publication: 2014 Mar 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0376340 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-8673 (Electronic) Linking ISSN: 00224804 NLM ISO Abbreviation: J Surg Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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