Multivalent presentation of MPL by porous silicon microparticles favors T helper 1 polarization enhancing the anti-tumor efficacy of doxorubicin nanoliposomes.

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Title: Multivalent presentation of MPL by porous silicon microparticles favors T helper 1 polarization enhancing the anti-tumor efficacy of doxorubicin nanoliposomes.
Authors: Meraz IM; Nanomedicine, Houston Methodist Research Institute, Houston, Texas, United States of America., Hearnden CH; Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland., Liu X; Nanomedicine, Houston Methodist Research Institute, Houston, Texas, United States of America., Yang M; Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland; Advanced Materials and BioEngineering Research (AMBER), Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College, Dublin, Ireland., Williams L; Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland; Advanced Materials and BioEngineering Research (AMBER), Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College, Dublin, Ireland., Savage DJ; Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, United States of America; The University of Texas School of Medicine, Houston, Texas, United States of America., Gu J; Nanomedicine, Houston Methodist Research Institute, Houston, Texas, United States of America., Rhudy JR; Nanomedicine, Houston Methodist Research Institute, Houston, Texas, United States of America., Yokoi K; Nanomedicine, Houston Methodist Research Institute, Houston, Texas, United States of America., Lavelle EC; Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College, Dublin, Ireland; Advanced Materials and BioEngineering Research (AMBER), Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College, Dublin, Ireland., Serda RE; Nanomedicine, Houston Methodist Research Institute, Houston, Texas, United States of America; Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, United States of America.
Source: PloS one [PLoS One] 2014 Apr 15; Vol. 9 (4), pp. e94703. Date of Electronic Publication: 2014 Apr 15 (Print Publication: 2014).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1932-6203
DOI:10.1371/journal.pone.0094703