An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.
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| Title: | An integrin β₃-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition. |
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| Authors: | Seguin L; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Kato S; School of Medicine, Division of Hematology/Oncology, University of California, San Diego, La Jolla, California 92093, USA., Franovic A; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Camargo MF; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Lesperance J; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Elliott KC; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Yebra M; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Mielgo A; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Lowy AM; Division of Surgical Oncology, Departments of Surgery, San Diego, La Jolla, California 92093, USA., Husain H; School of Medicine, Division of Hematology/Oncology, University of California, San Diego, La Jolla, California 92093, USA., Cascone T; Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA., Diao L; Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA., Wang J; Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA., Wistuba II; Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA., Heymach JV; Departments of Thoracic/Head and Neck Medical Oncology and Cancer Biology, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA., Lippman SM; Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Desgrosellier JS; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Anand S; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Weis SM; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA., Cheresh DA; Department of Pathology and Moores UCSD Cancer Center, University of California, San Diego, La Jolla, California 92093, USA. |
| Source: | Nature cell biology [Nat Cell Biol] 2014 May; Vol. 16 (5), pp. 457-68. Date of Electronic Publication: 2014 Apr 20. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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