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Mechanism of action and epitopes of Clostridium difficile toxin B-neutralizing antibody bezlotoxumab revealed by X-ray crystallography.

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Title: Mechanism of action and epitopes of Clostridium difficile toxin B-neutralizing antibody bezlotoxumab revealed by X-ray crystallography.
Authors: Orth P; From Merck & Co., Inc., Kenilworth, New Jersey 07023., Xiao L; From Merck & Co., Inc., Kenilworth, New Jersey 07023., Hernandez LD; From Merck & Co., Inc., Kenilworth, New Jersey 07023., Reichert P; From Merck & Co., Inc., Kenilworth, New Jersey 07023., Sheth PR; From Merck & Co., Inc., Kenilworth, New Jersey 07023., Beaumont M; Merck & Co., Inc., Palo Alto, California 94304, and., Yang X; From Merck & Co., Inc., Kenilworth, New Jersey 07023., Murgolo N; From Merck & Co., Inc., Kenilworth, New Jersey 07023., Ermakov G; Merck & Co., Inc., Palo Alto, California 94304, and., DiNunzio E; From Merck & Co., Inc., Kenilworth, New Jersey 07023., Racine F; From Merck & Co., Inc., Kenilworth, New Jersey 07023., Karczewski J; Merck & Co., Inc., West Point, Pennsylvania 19486., Secore S; Merck & Co., Inc., West Point, Pennsylvania 19486., Ingram RN; From Merck & Co., Inc., Kenilworth, New Jersey 07023., Mayhood T; From Merck & Co., Inc., Kenilworth, New Jersey 07023., Strickland C; From Merck & Co., Inc., Kenilworth, New Jersey 07023, corey.strickland@merck.com., Therien AG; From Merck & Co., Inc., Kenilworth, New Jersey 07023, alex_therien@merck.com.
Source: The Journal of biological chemistry [J Biol Chem] 2014 Jun 27; Vol. 289 (26), pp. 18008-21. Date of Electronic Publication: 2014 May 12.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mechanism of action and epitopes of Clostridium difficile toxin B-neutralizing antibody bezlotoxumab revealed by X-ray crystallography.
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  Data: <searchLink fieldCode="JN" term="%222985121R%22">The Journal of biological chemistry</searchLink> [J Biol Chem] 2014 Jun 27; Vol. 289 (26), pp. 18008-21. <i>Date of Electronic Publication: </i>2014 May 12.
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        Value: 10.1074/jbc.M114.560748
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              Text: 2014 Jun 27
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