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Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.

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Title: Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.
Authors: Pfaffeneder T; 1] Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany. [2]., Spada F; 1] Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany. [2]., Wagner M; 1] Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany. [2]., Brandmayr C; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany., Laube SK; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany., Eisen D; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany., Truss M; Charité Universitätsklinikum, Otto-Heubner-Centrum für Kinder und Jugendmedizin, Klinik für Allgemeine Pädiatrie, Labor für Pädiatrische Molekularbiologie, Berlin, Germany., Steinbacher J; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany., Hackner B; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany., Kotljarova O; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany., Schuermann D; Department of Biomedicine, University of Basel, Basel, Switzerland., Michalakis S; Center for Integrated Protein Science at the Department of Pharmacy-Center for Drug Research, Ludwig-Maximilians-Universität München, München, Germany., Kosmatchev O; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany., Schiesser S; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany., Steigenberger B; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany., Raddaoui N; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany., Kashiwazaki G; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany., Müller U; Center for Integrated Protein Science at the Department of Biology, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany., Spruijt CG; Department of Molecular Cancer Research, Cancer Genomics Netherlands, Utrecht, The Netherlands., Vermeulen M; 1] Department of Molecular Cancer Research, Cancer Genomics Netherlands, Utrecht, The Netherlands. [2]., Leonhardt H; Center for Integrated Protein Science at the Department of Biology, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany., Schär P; Department of Biomedicine, University of Basel, Basel, Switzerland., Müller M; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany., Carell T; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany.
Source: Nature chemical biology [Nat Chem Biol] 2014 Jul; Vol. 10 (7), pp. 574-81. Date of Electronic Publication: 2014 May 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE
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  Data: Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.
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  Data: <searchLink fieldCode="AU" term="%22Pfaffeneder+T%22">Pfaffeneder T</searchLink>; 1] Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany. [2].<br /><searchLink fieldCode="AU" term="%22Spada+F%22">Spada F</searchLink>; 1] Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany. [2].<br /><searchLink fieldCode="AU" term="%22Wagner+M%22">Wagner M</searchLink>; 1] Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany. [2].<br /><searchLink fieldCode="AU" term="%22Brandmayr+C%22">Brandmayr C</searchLink>; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany.<br /><searchLink fieldCode="AU" term="%22Laube+SK%22">Laube SK</searchLink>; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany.<br /><searchLink fieldCode="AU" term="%22Eisen+D%22">Eisen D</searchLink>; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany.<br /><searchLink fieldCode="AU" term="%22Truss+M%22">Truss M</searchLink>; Charité Universitätsklinikum, Otto-Heubner-Centrum für Kinder und Jugendmedizin, Klinik für Allgemeine Pädiatrie, Labor für Pädiatrische Molekularbiologie, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Steinbacher+J%22">Steinbacher J</searchLink>; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany.<br /><searchLink fieldCode="AU" term="%22Hackner+B%22">Hackner B</searchLink>; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany.<br /><searchLink fieldCode="AU" term="%22Kotljarova+O%22">Kotljarova O</searchLink>; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany.<br /><searchLink fieldCode="AU" term="%22Schuermann+D%22">Schuermann D</searchLink>; Department of Biomedicine, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Michalakis+S%22">Michalakis S</searchLink>; Center for Integrated Protein Science at the Department of Pharmacy-Center for Drug Research, Ludwig-Maximilians-Universität München, München, Germany.<br /><searchLink fieldCode="AU" term="%22Kosmatchev+O%22">Kosmatchev O</searchLink>; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany.<br /><searchLink fieldCode="AU" term="%22Schiesser+S%22">Schiesser S</searchLink>; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany.<br /><searchLink fieldCode="AU" term="%22Steigenberger+B%22">Steigenberger B</searchLink>; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany.<br /><searchLink fieldCode="AU" term="%22Raddaoui+N%22">Raddaoui N</searchLink>; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany.<br /><searchLink fieldCode="AU" term="%22Kashiwazaki+G%22">Kashiwazaki G</searchLink>; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany.<br /><searchLink fieldCode="AU" term="%22Müller+U%22">Müller U</searchLink>; Center for Integrated Protein Science at the Department of Biology, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany.<br /><searchLink fieldCode="AU" term="%22Spruijt+CG%22">Spruijt CG</searchLink>; Department of Molecular Cancer Research, Cancer Genomics Netherlands, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Vermeulen+M%22">Vermeulen M</searchLink>; 1] Department of Molecular Cancer Research, Cancer Genomics Netherlands, Utrecht, The Netherlands. [2].<br /><searchLink fieldCode="AU" term="%22Leonhardt+H%22">Leonhardt H</searchLink>; Center for Integrated Protein Science at the Department of Biology, Ludwig-Maximilians-Universität München, Planegg-Martinsried, Germany.<br /><searchLink fieldCode="AU" term="%22Schär+P%22">Schär P</searchLink>; Department of Biomedicine, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Müller+M%22">Müller M</searchLink>; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany.<br /><searchLink fieldCode="AU" term="%22Carell+T%22">Carell T</searchLink>; Center for Integrated Protein Science at the Department of Chemistry, Ludwig-Maximilians-Universität München, München, Germany.
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