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SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.

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Title: SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.
Authors: Mazur PK; 1] Department of Pediatrics, Stanford University School of Medicine, California 94305, USA [2] Department of Genetics, Stanford University School of Medicine, California 94305, USA [3]., Reynoird N; 1] Department of Biology, Stanford University, California 94305, USA [2]., Khatri P; Institute for Immunity, Transplantation and Infection, and Department of Medicine, Stanford University School of Medicine, California 94305, USA., Jansen PW; Department of Molecular Cancer Research and Department of Medical Oncology, University Medical Center Utrecht, 3508 AB Utrecht, The Netherlands., Wilkinson AW; Department of Biology, Stanford University, California 94305, USA., Liu S; Epigenetics Program and Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA., Barbash O; Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA., Van Aller GS; Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA., Huddleston M; Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA., Dhanak D; 1] Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA [2] Janssen Research and Development, 1400 McKean Road, Spring House, Pennsylvania 19477, USA (D.D.); Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University, 6525GA Nijmegen, The Netherlands (M.V.)., Tummino PJ; Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA., Kruger RG; Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA., Garcia BA; Epigenetics Program and Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA., Butte AJ; 1] Department of Pediatrics, Stanford University School of Medicine, California 94305, USA [2] Department of Genetics, Stanford University School of Medicine, California 94305, USA., Vermeulen M; 1] Department of Molecular Cancer Research and Department of Medical Oncology, University Medical Center Utrecht, 3508 AB Utrecht, The Netherlands [2] Janssen Research and Development, 1400 McKean Road, Spring House, Pennsylvania 19477, USA (D.D.); Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University, 6525GA Nijmegen, The Netherlands (M.V.)., Sage J; 1] Department of Pediatrics, Stanford University School of Medicine, California 94305, USA [2] Department of Genetics, Stanford University School of Medicine, California 94305, USA [3]., Gozani O; 1] Department of Biology, Stanford University, California 94305, USA [2].
Source: Nature [Nature] 2014 Jun 12; Vol. 510 (7504), pp. 283-7. Date of Electronic Publication: 2014 May 21.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer.
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  Data: <searchLink fieldCode="AU" term="%22Mazur+PK%22">Mazur PK</searchLink>; 1] Department of Pediatrics, Stanford University School of Medicine, California 94305, USA [2] Department of Genetics, Stanford University School of Medicine, California 94305, USA [3].<br /><searchLink fieldCode="AU" term="%22Reynoird+N%22">Reynoird N</searchLink>; 1] Department of Biology, Stanford University, California 94305, USA [2].<br /><searchLink fieldCode="AU" term="%22Khatri+P%22">Khatri P</searchLink>; Institute for Immunity, Transplantation and Infection, and Department of Medicine, Stanford University School of Medicine, California 94305, USA.<br /><searchLink fieldCode="AU" term="%22Jansen+PW%22">Jansen PW</searchLink>; Department of Molecular Cancer Research and Department of Medical Oncology, University Medical Center Utrecht, 3508 AB Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Wilkinson+AW%22">Wilkinson AW</searchLink>; Department of Biology, Stanford University, California 94305, USA.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Epigenetics Program and Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.<br /><searchLink fieldCode="AU" term="%22Barbash+O%22">Barbash O</searchLink>; Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA.<br /><searchLink fieldCode="AU" term="%22Van+Aller+GS%22">Van Aller GS</searchLink>; Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA.<br /><searchLink fieldCode="AU" term="%22Huddleston+M%22">Huddleston M</searchLink>; Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA.<br /><searchLink fieldCode="AU" term="%22Dhanak+D%22">Dhanak D</searchLink>; 1] Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA [2] Janssen Research and Development, 1400 McKean Road, Spring House, Pennsylvania 19477, USA (D.D.); Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University, 6525GA Nijmegen, The Netherlands (M.V.).<br /><searchLink fieldCode="AU" term="%22Tummino+PJ%22">Tummino PJ</searchLink>; Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA.<br /><searchLink fieldCode="AU" term="%22Kruger+RG%22">Kruger RG</searchLink>; Cancer Epigenetics DPU, Oncology R&D, GlaxoSmithKline, Collegeville, Pennsylvania 19426 USA.<br /><searchLink fieldCode="AU" term="%22Garcia+BA%22">Garcia BA</searchLink>; Epigenetics Program and Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.<br /><searchLink fieldCode="AU" term="%22Butte+AJ%22">Butte AJ</searchLink>; 1] Department of Pediatrics, Stanford University School of Medicine, California 94305, USA [2] Department of Genetics, Stanford University School of Medicine, California 94305, USA.<br /><searchLink fieldCode="AU" term="%22Vermeulen+M%22">Vermeulen M</searchLink>; 1] Department of Molecular Cancer Research and Department of Medical Oncology, University Medical Center Utrecht, 3508 AB Utrecht, The Netherlands [2] Janssen Research and Development, 1400 McKean Road, Spring House, Pennsylvania 19477, USA (D.D.); Department of Molecular Biology, Faculty of Science, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University, 6525GA Nijmegen, The Netherlands (M.V.).<br /><searchLink fieldCode="AU" term="%22Sage+J%22">Sage J</searchLink>; 1] Department of Pediatrics, Stanford University School of Medicine, California 94305, USA [2] Department of Genetics, Stanford University School of Medicine, California 94305, USA [3].<br /><searchLink fieldCode="AU" term="%22Gozani+O%22">Gozani O</searchLink>; 1] Department of Biology, Stanford University, California 94305, USA [2].
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2014 Jun 12; Vol. 510 (7504), pp. 283-7. <i>Date of Electronic Publication: </i>2014 May 21.
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