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Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.

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Title: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.
Authors: Wang Y; 1] Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK. [2]., McKay JD; 1] International Agency for Research on Cancer (IARC, World Health Organization (WHO)), Lyon, France. [2] [3]., Rafnar T; deCODE Genetics, Amgen, Reykjavik, Iceland., Wang Z; Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA., Timofeeva MN; International Agency for Research on Cancer (IARC, World Health Organization (WHO)), Lyon, France., Broderick P; Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK., Zong X; Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada., Laplana M; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany., Wei Y; Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA., Han Y; Center for Genomic Medicine, Department of Community and Family Medicine, Geisel School of Medicine, Dartmouth College, Lebanon, New Hampshire, USA., Lloyd A; Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK., Delahaye-Sourdeix M; International Agency for Research on Cancer (IARC, World Health Organization (WHO)), Lyon, France., Chubb D; Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK., Gaborieau V; International Agency for Research on Cancer (IARC, World Health Organization (WHO)), Lyon, France., Wheeler W; Information Management Services, Inc., Rockville, Maryland, USA., Chatterjee N; Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA., Thorleifsson G; deCODE Genetics, Amgen, Reykjavik, Iceland., Sulem P; deCODE Genetics, Amgen, Reykjavik, Iceland., Liu G; Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada., Kaaks R; 1] Division of Cancer Epidemiology, DKFZ, Heidelberg, Germany. [2] Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany., Henrion M; Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK., Kinnersley B; Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK., Vallée M; International Agency for Research on Cancer (IARC, World Health Organization (WHO)), Lyon, France., LeCalvez-Kelm F; International Agency for Research on Cancer (IARC, World Health Organization (WHO)), Lyon, France., Stevens VL; Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA., Gapstur SM; Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA., Chen WV; Department of Genetics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Zaridze D; Institute of Carcinogenesis, Russian N.N. Blokhin Cancer Research Centre, Moscow, Russia., Szeszenia-Dabrowska N; Department of Epidemiology, Institute of Occupational Medicine, Lodz, Poland., Lissowska J; The M. Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland., Rudnai P; National Institute of Environmental Health, Budapest, Hungary., Fabianova E; Regional Authority of Public Health, Banská Bystrica, Slovak Republic., Mates D; National Institute of Public Health, Bucharest, Romania., Bencko V; 1st Faculty of Medicine, Institute of Hygiene and Epidemiology, Charles University in Prague, Prague, Czech Republic., Foretova L; Department of Cancer Epidemiology and Genetics, Masaryk Memorial Cancer Institute, Brno, Czech Republic., Janout V; Palacky University, Olomouc, Czech Republic., Krokan HE; Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway., Gabrielsen ME; Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway., Skorpen F; Department of Laboratory Medicine, Children's and Women's Health, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Vatten L; Department of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway., Njølstad I; Department of Community Medicine, University of Tromsø, Tromsø, Norway., Chen C; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Goodman G; Fred Hutchinson Cancer Research Center, Seattle, Washington, USA., Benhamou S; INSERM U946, Paris, France., Vooder T; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Välk K; Department of Biomedicine, University of Bergen, Bergen, Norway., Nelis M; 1] Estonian Genome Center, Institute of Molecular and Cell Biology, Tartu, Estonia. [2] Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland., Metspalu A; Estonian Genome Center, Institute of Molecular and Cell Biology, Tartu, Estonia., Lener M; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland., Lubiński J; Department of Genetics and Pathology, International Hereditary Cancer Center, Pomeranian Medical University, Szczecin, Poland., Johansson M; International Agency for Research on Cancer (IARC, World Health Organization (WHO)), Lyon, France., Vineis P; 1] Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, UK. [2] Unit of Molecular and Genetic Epidemiology, HuGeF Foundation, Torino, Italy., Agudo A; Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Program, Catalan Institute of Oncology, Barcelona, Spain., Clavel-Chapelon F; 1] INSERM, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team, Villejuif, France. [2] Université Paris Sud, UMRS 1018, Villejuif, France. [3] Institut Gustave Roussy, Villejuif, France., Bueno-de-Mesquita HB; 1] Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, UK. [2] National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands. [3] Department of Gastroenterology and Hepatology, University Medical Centre, Utrecht, The Netherlands., Trichopoulos D; 1] Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA. [2] Bureau of Epidemiologic Research, Academy of Athens, Athens, Greece. [3] Hellenic Health Foundation, Athens, Greece., Khaw KT; University of Cambridge School of Clinical Medicine, Clinical Gerontology Unit, Addenbrooke's Hospital, Cambridge, UK., Johansson M; Department of Radiation Sciences, Umeå Universitet, Umeå, Sverige, Sweden., Weiderpass E; 1] Department of Community Medicine, Faculty of Health Sciences, University of Tromsø, Tromsø, Norway. [2] Department of Research, Cancer Registry of Norway, Oslo, Norway. [3] Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. [4] Samfundet Folkhälsan, Helsinki, Finland., Tjønneland A; Danish Cancer Society Research Center, Copenhagen, Denmark., Riboli E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College, London, UK., Lathrop M; Centre d'Etude du Polymorphisme Humain (CEPH), Paris, France., Scelo G; International Agency for Research on Cancer (IARC, World Health Organization (WHO)), Lyon, France., Albanes D; Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA., Caporaso NE; Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA., Ye Y; Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Gu J; Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Wu X; Department of Epidemiology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Spitz MR; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas, USA., Dienemann H; 1] Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany. [2] Department of Thoracic Surgery, Thoraxklinik at University Hospital Heidelberg, Heidelberg, Germany., Rosenberger A; Department of Genetic Epidemiology, University of Göttingen, Göttingen, Germany., Su L; Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA., Matakidou A; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, Cambridge, UK., Eisen T; 1] Department of Oncology, Cambridge University Hospitals National Health Service Foundation Trust, Cambridge, UK. [2] Addenbrooke's Hospital, Cambridge Biomedical Campus, Cambridge, UK., Stefansson K; deCODE Genetics, Amgen, Reykjavik, Iceland., Risch A; 1] Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany. [2] Translational Lung Research Center Heidelberg (TLRC-H), Member of the German Center for Lung Research (DZL), Heidelberg, Germany., Chanock SJ; Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA., Christiani DC; Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA., Hung RJ; Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada., Brennan P; International Agency for Research on Cancer (IARC, World Health Organization (WHO)), Lyon, France., Landi MT; 1] Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA. [2] [3]., Houlston RS; 1] Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK. [2] [3]., Amos CI; 1] Center for Genomic Medicine, Department of Community and Family Medicine, Geisel School of Medicine, Dartmouth College, Lebanon, New Hampshire, USA. [2] [3].
Source: Nature genetics [Nat Genet] 2014 Jul; Vol. 46 (7), pp. 736-41. Date of Electronic Publication: 2014 Jun 01.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.
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  Data: <searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; 1] Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK. [2].<br /><searchLink fieldCode="AU" term="%22McKay+JD%22">McKay JD</searchLink>; 1] International Agency for Research on Cancer (IARC, World Health Organization (WHO)), Lyon, France. [2] [3].<br /><searchLink fieldCode="AU" term="%22Rafnar+T%22">Rafnar T</searchLink>; deCODE Genetics, Amgen, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Timofeeva+MN%22">Timofeeva MN</searchLink>; International Agency for Research on Cancer (IARC, World Health Organization (WHO)), Lyon, France.<br /><searchLink fieldCode="AU" term="%22Broderick+P%22">Broderick P</searchLink>; Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK.<br /><searchLink fieldCode="AU" term="%22Zong+X%22">Zong X</searchLink>; Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Laplana+M%22">Laplana M</searchLink>; Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Wei+Y%22">Wei Y</searchLink>; Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Han+Y%22">Han Y</searchLink>; Center for Genomic Medicine, Department of Community and Family Medicine, Geisel School of Medicine, Dartmouth College, Lebanon, New Hampshire, USA.<br /><searchLink fieldCode="AU" term="%22Lloyd+A%22">Lloyd A</searchLink>; Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK.<br /><searchLink fieldCode="AU" term="%22Delahaye-Sourdeix+M%22">Delahaye-Sourdeix M</searchLink>; International Agency for Research on Cancer (IARC, World Health Organization (WHO)), Lyon, France.<br /><searchLink fieldCode="AU" term="%22Chubb+D%22">Chubb D</searchLink>; Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK.<br /><searchLink fieldCode="AU" term="%22Gaborieau+V%22">Gaborieau V</searchLink>; International Agency for Research on Cancer (IARC, World Health Organization (WHO)), Lyon, France.<br /><searchLink fieldCode="AU" term="%22Wheeler+W%22">Wheeler W</searchLink>; Information Management Services, Inc., Rockville, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Chatterjee+N%22">Chatterjee N</searchLink>; Department of Health and Human Services, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Thorleifsson+G%22">Thorleifsson G</searchLink>; deCODE Genetics, Amgen, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Sulem+P%22">Sulem P</searchLink>; deCODE Genetics, Amgen, Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Liu+G%22">Liu G</searchLink>; Princess Margaret Hospital, University Health Network, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Kaaks+R%22">Kaaks R</searchLink>; 1] Division of Cancer Epidemiology, DKFZ, Heidelberg, Germany. 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[2] [3].<br /><searchLink fieldCode="AU" term="%22Houlston+RS%22">Houlston RS</searchLink>; 1] Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK. [2] [3].<br /><searchLink fieldCode="AU" term="%22Amos+CI%22">Amos CI</searchLink>; 1] Center for Genomic Medicine, Department of Community and Family Medicine, Geisel School of Medicine, Dartmouth College, Lebanon, New Hampshire, USA. [2] [3].
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  Data: <searchLink fieldCode="JN" term="%229216904%22">Nature genetics</searchLink> [Nat Genet] 2014 Jul; Vol. 46 (7), pp. 736-41. <i>Date of Electronic Publication: </i>2014 Jun 01.
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      – TitleFull: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer.
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            – D: 01
              M: 07
              Text: 2014 Jul
              Type: published
              Y: 2014
          Identifiers:
            – Type: issn-electronic
              Value: 1546-1718
          Numbering:
            – Type: volume
              Value: 46
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Nature genetics
              Type: main
ResultId 1