In vivo co-localization of enzymes on RNA scaffolds increases metabolic production in a geometrically dependent manner.

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Title: In vivo co-localization of enzymes on RNA scaffolds increases metabolic production in a geometrically dependent manner.
Authors: Sachdeva G; School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA Wyss Institute for Biologically Inspired Engineering, 3 Blackfan St., Boston, MA 02115, USA., Garg A; Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA., Godding D; Department of Life Sciences, Imperial College London, London SW7 2AZ, UK., Way JC; Wyss Institute for Biologically Inspired Engineering, 3 Blackfan St., Boston, MA 02115, USA., Silver PA; Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA Wyss Institute for Biologically Inspired Engineering, 3 Blackfan St., Boston, MA 02115, USA pamela_silver@hms.harvard.edu.
Source: Nucleic acids research [Nucleic Acids Res] 2014 Aug; Vol. 42 (14), pp. 9493-503. Date of Electronic Publication: 2014 Jul 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: In vivo co-localization of enzymes on RNA scaffolds increases metabolic production in a geometrically dependent manner.
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  Data: <searchLink fieldCode="AU" term="%22Sachdeva+G%22">Sachdeva G</searchLink>; School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA Wyss Institute for Biologically Inspired Engineering, 3 Blackfan St., Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Garg+A%22">Garg A</searchLink>; Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Godding+D%22">Godding D</searchLink>; Department of Life Sciences, Imperial College London, London SW7 2AZ, UK.<br /><searchLink fieldCode="AU" term="%22Way+JC%22">Way JC</searchLink>; Wyss Institute for Biologically Inspired Engineering, 3 Blackfan St., Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Silver+PA%22">Silver PA</searchLink>; Department of Systems Biology, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA Wyss Institute for Biologically Inspired Engineering, 3 Blackfan St., Boston, MA 02115, USA pamela_silver@hms.harvard.edu.
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        Value: 10.1093/nar/gku617
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              Text: 2014 Aug
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