Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms.
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| Title: | Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms. |
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| Authors: | Calabrese MF; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Rajamohan F; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Harris MS; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Caspers NL; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Magyar R; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Withka JM; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Wang H; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Borzilleri KA; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Sahasrabudhe PV; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Hoth LR; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Geoghegan KF; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Han S; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Brown J; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Subashi TA; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Reyes AR; Worldwide Research and Development, Pfizer Inc., 610 Main Street, Cambridge, MA 02139, USA., Frisbie RK; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Ward J; Worldwide Research and Development, Pfizer Inc., 610 Main Street, Cambridge, MA 02139, USA., Miller RA; Worldwide Research and Development, Pfizer Inc., 610 Main Street, Cambridge, MA 02139, USA., Landro JA; Worldwide Research and Development, Pfizer Inc., 610 Main Street, Cambridge, MA 02139, USA., Londregan AT; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Carpino PA; Worldwide Research and Development, Pfizer Inc., 610 Main Street, Cambridge, MA 02139, USA., Cabral S; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Smith AC; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Conn EL; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Cameron KO; Worldwide Research and Development, Pfizer Inc., 610 Main Street, Cambridge, MA 02139, USA., Qiu X; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Kurumbail RG; Worldwide Research and Development, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA. Electronic address: ravi.g.kurumbail@pfizer.com. |
| Source: | Structure (London, England : 1993) [Structure] 2014 Aug 05; Vol. 22 (8), pp. 1161-1172. Date of Electronic Publication: 2014 Jul 24. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101087697 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4186 (Electronic) Linking ISSN: 09692126 NLM ISO Abbreviation: Structure Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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