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Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA.

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Title: Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA.
Authors: Cortes CJ; 1] Department of Pediatrics, University of California, San Diego, La Jolla, California, USA. [2]., Miranda HC; 1] Department of Pediatrics, University of California, San Diego, La Jolla, California, USA. [2] Department of Cellular &Molecular Medicine, University of California, San Diego, La Jolla, California, USA. [3]., Frankowski H; Department of Pediatrics, University of California, San Diego, La Jolla, California, USA., Batlevi Y; Department of Pediatrics, University of California, San Diego, La Jolla, California, USA., Young JE; Department of Cellular &Molecular Medicine, University of California, San Diego, La Jolla, California, USA., Le A; Department of Pediatrics, University of California, San Diego, La Jolla, California, USA., Ivanov N; 1] Center on Human Development &Disability, University of Washington, Seattle, Washington, USA. [2] Department of Neurology, University of Washington, Seattle, Washington, USA., Sopher BL; Department of Neurology, University of Washington, Seattle, Washington, USA., Carromeu C; Department of Pediatrics, University of California, San Diego, La Jolla, California, USA., Muotri AR; 1] Department of Pediatrics, University of California, San Diego, La Jolla, California, USA. [2] Department of Cellular &Molecular Medicine, University of California, San Diego, La Jolla, California, USA. [3] Department of Neurosciences, University of California, San Diego, La Jolla, California, USA. [4] Institute for Genomic Medicine, University of California, San Diego, La Jolla, California, USA. [5] Sanford Consortium for Regenerative Medicine, University of California, San Diego, La Jolla, California, USA. [6] Rady Children's Hospital, San Diego, California, USA., Garden GA; 1] Center on Human Development &Disability, University of Washington, Seattle, Washington, USA. [2] Department of Neurology, University of Washington, Seattle, Washington, USA., La Spada AR; 1] Department of Pediatrics, University of California, San Diego, La Jolla, California, USA. [2] Department of Cellular &Molecular Medicine, University of California, San Diego, La Jolla, California, USA. [3] Department of Neurosciences, University of California, San Diego, La Jolla, California, USA. [4] Institute for Genomic Medicine, University of California, San Diego, La Jolla, California, USA. [5] Sanford Consortium for Regenerative Medicine, University of California, San Diego, La Jolla, California, USA. [6] Rady Children's Hospital, San Diego, California, USA. [7] Division of Biological Sciences, University of California, San Diego, La Jolla, California, USA.
Source: Nature neuroscience [Nat Neurosci] 2014 Sep; Vol. 17 (9), pp. 1180-9. Date of Electronic Publication: 2014 Aug 10.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA.
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  Data: <searchLink fieldCode="AU" term="%22Cortes+CJ%22">Cortes CJ</searchLink>; 1] Department of Pediatrics, University of California, San Diego, La Jolla, California, USA. [2].<br /><searchLink fieldCode="AU" term="%22Miranda+HC%22">Miranda HC</searchLink>; 1] Department of Pediatrics, University of California, San Diego, La Jolla, California, USA. [2] Department of Cellular &Molecular Medicine, University of California, San Diego, La Jolla, California, USA. [3].<br /><searchLink fieldCode="AU" term="%22Frankowski+H%22">Frankowski H</searchLink>; Department of Pediatrics, University of California, San Diego, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Batlevi+Y%22">Batlevi Y</searchLink>; Department of Pediatrics, University of California, San Diego, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Young+JE%22">Young JE</searchLink>; Department of Cellular &Molecular Medicine, University of California, San Diego, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Le+A%22">Le A</searchLink>; Department of Pediatrics, University of California, San Diego, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Ivanov+N%22">Ivanov N</searchLink>; 1] Center on Human Development &Disability, University of Washington, Seattle, Washington, USA. [2] Department of Neurology, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Sopher+BL%22">Sopher BL</searchLink>; Department of Neurology, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22Carromeu+C%22">Carromeu C</searchLink>; Department of Pediatrics, University of California, San Diego, La Jolla, California, USA.<br /><searchLink fieldCode="AU" term="%22Muotri+AR%22">Muotri AR</searchLink>; 1] Department of Pediatrics, University of California, San Diego, La Jolla, California, USA. [2] Department of Cellular &Molecular Medicine, University of California, San Diego, La Jolla, California, USA. [3] Department of Neurosciences, University of California, San Diego, La Jolla, California, USA. [4] Institute for Genomic Medicine, University of California, San Diego, La Jolla, California, USA. [5] Sanford Consortium for Regenerative Medicine, University of California, San Diego, La Jolla, California, USA. [6] Rady Children's Hospital, San Diego, California, USA.<br /><searchLink fieldCode="AU" term="%22Garden+GA%22">Garden GA</searchLink>; 1] Center on Human Development &Disability, University of Washington, Seattle, Washington, USA. [2] Department of Neurology, University of Washington, Seattle, Washington, USA.<br /><searchLink fieldCode="AU" term="%22La+Spada+AR%22">La Spada AR</searchLink>; 1] Department of Pediatrics, University of California, San Diego, La Jolla, California, USA. [2] Department of Cellular &Molecular Medicine, University of California, San Diego, La Jolla, California, USA. [3] Department of Neurosciences, University of California, San Diego, La Jolla, California, USA. [4] Institute for Genomic Medicine, University of California, San Diego, La Jolla, California, USA. [5] Sanford Consortium for Regenerative Medicine, University of California, San Diego, La Jolla, California, USA. [6] Rady Children's Hospital, San Diego, California, USA. [7] Division of Biological Sciences, University of California, San Diego, La Jolla, California, USA.
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  Data: <searchLink fieldCode="JN" term="%229809671%22">Nature neuroscience</searchLink> [Nat Neurosci] 2014 Sep; Vol. 17 (9), pp. 1180-9. <i>Date of Electronic Publication: </i>2014 Aug 10.
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