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Somatotropinomas, but not nonfunctioning pituitary adenomas, maintain a functional apoptotic RET/Pit1/ARF/p53 pathway that is blocked by excess GDNF.

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Title: Somatotropinomas, but not nonfunctioning pituitary adenomas, maintain a functional apoptotic RET/Pit1/ARF/p53 pathway that is blocked by excess GDNF.
Authors: Diaz-Rodriguez E; Centre for Investigations in Medicine of the USC (E.D.-R., A.R.G.-G., M.G.-L., C.D., C.V.A.), University of Santiago de Compostela, Santiago de Compostela, Spain 15782; Department of Endocrinology (I.B.), University Hospital (University Hospital of Santiago de Compostela), Instituto de Investigación Sanitaria, Santiago de Compostela, Spain 15706; Departments of Cell Biology, Physiology, and Immunology (A.I.-C., E.G.-P., R.M.L., J.P.C.), and Morphological Sciences (L.J.-R.), University of Cordoba, and Reina Sofia University Hospital (P.B., M.A.G.), Maimonides Institute for Research in Biomedicine of Cordoba, Córdoba, Spain 14014; Departments of Endocrinology and Pathology (A.L., M.A.J., A.S., E.V.), Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla, University of Sevilla, Sevilla, Spain 41013; Department of Endocrinology (F.J.T.), Hospital Virgen de la Victoria, and Department of Endocrinology (J.A.G.-A.), Hospital Carlos Haya, Malaga, Spain 29010; and CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn) 15706, spain (A.I.-C., F.J.T., P.B., I.B., C.D., R.M.L., J.P.C., C.V.A.), Spain 15706., Garcia-Rendueles AR, Ibáñez-Costa A, Gutierrez-Pascual E, Garcia-Lavandeira M, Leal A, Japon MA, Soto A, Venegas E, Tinahones FJ, Garcia-Arnes JA, Benito P, Angeles Galvez M, Jimenez-Reina L, Bernabeu I, Dieguez C, Luque RM, Castaño JP, Alvarez CV
Source: Endocrinology [Endocrinology] 2014 Nov; Vol. 155 (11), pp. 4329-40. Date of Electronic Publication: 2014 Aug 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375040 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1945-7170 (Electronic) Linking ISSN: 00137227 NLM ISO Abbreviation: Endocrinology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Somatotropinomas, but not nonfunctioning pituitary adenomas, maintain a functional apoptotic RET/Pit1/ARF/p53 pathway that is blocked by excess GDNF.
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  Data: <searchLink fieldCode="AU" term="%22Diaz-Rodriguez+E%22">Diaz-Rodriguez E</searchLink>; Centre for Investigations in Medicine of the USC (E.D.-R., A.R.G.-G., M.G.-L., C.D., C.V.A.), University of Santiago de Compostela, Santiago de Compostela, Spain 15782; Department of Endocrinology (I.B.), University Hospital (University Hospital of Santiago de Compostela), Instituto de Investigación Sanitaria, Santiago de Compostela, Spain 15706; Departments of Cell Biology, Physiology, and Immunology (A.I.-C., E.G.-P., R.M.L., J.P.C.), and Morphological Sciences (L.J.-R.), University of Cordoba, and Reina Sofia University Hospital (P.B., M.A.G.), Maimonides Institute for Research in Biomedicine of Cordoba, Córdoba, Spain 14014; Departments of Endocrinology and Pathology (A.L., M.A.J., A.S., E.V.), Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla, University of Sevilla, Sevilla, Spain 41013; Department of Endocrinology (F.J.T.), Hospital Virgen de la Victoria, and Department of Endocrinology (J.A.G.-A.), Hospital Carlos Haya, Malaga, Spain 29010; and CIBER Fisiopatología de la Obesidad y Nutrición (CIBERobn) 15706, spain (A.I.-C., F.J.T., P.B., I.B., C.D., R.M.L., J.P.C., C.V.A.), Spain 15706.<br /><searchLink fieldCode="AU" term="%22Garcia-Rendueles+AR%22">Garcia-Rendueles AR</searchLink><br /><searchLink fieldCode="AU" term="%22Ibáñez-Costa+A%22">Ibáñez-Costa A</searchLink><br /><searchLink fieldCode="AU" term="%22Gutierrez-Pascual+E%22">Gutierrez-Pascual E</searchLink><br /><searchLink fieldCode="AU" term="%22Garcia-Lavandeira+M%22">Garcia-Lavandeira M</searchLink><br /><searchLink fieldCode="AU" term="%22Leal+A%22">Leal A</searchLink><br /><searchLink fieldCode="AU" term="%22Japon+MA%22">Japon MA</searchLink><br /><searchLink fieldCode="AU" term="%22Soto+A%22">Soto A</searchLink><br /><searchLink fieldCode="AU" term="%22Venegas+E%22">Venegas E</searchLink><br /><searchLink fieldCode="AU" term="%22Tinahones+FJ%22">Tinahones FJ</searchLink><br /><searchLink fieldCode="AU" term="%22Garcia-Arnes+JA%22">Garcia-Arnes JA</searchLink><br /><searchLink fieldCode="AU" term="%22Benito+P%22">Benito P</searchLink><br /><searchLink fieldCode="AU" term="%22Angeles+Galvez+M%22">Angeles Galvez M</searchLink><br /><searchLink fieldCode="AU" term="%22Jimenez-Reina+L%22">Jimenez-Reina L</searchLink><br /><searchLink fieldCode="AU" term="%22Bernabeu+I%22">Bernabeu I</searchLink><br /><searchLink fieldCode="AU" term="%22Dieguez+C%22">Dieguez C</searchLink><br /><searchLink fieldCode="AU" term="%22Luque+RM%22">Luque RM</searchLink><br /><searchLink fieldCode="AU" term="%22Castaño+JP%22">Castaño JP</searchLink><br /><searchLink fieldCode="AU" term="%22Alvarez+CV%22">Alvarez CV</searchLink>
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  Data: <searchLink fieldCode="JN" term="%220375040%22">Endocrinology</searchLink> [Endocrinology] 2014 Nov; Vol. 155 (11), pp. 4329-40. <i>Date of Electronic Publication: </i>2014 Aug 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0375040 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1945-7170 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200137227%22">00137227 </searchLink><i>NLM ISO Abbreviation: </i>Endocrinology <i>Subsets: </i>MEDLINE
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