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Fragment-based screening in tandem with phenotypic screening provides novel antiparasitic hits.

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Bibliographic Details
Title: Fragment-based screening in tandem with phenotypic screening provides novel antiparasitic hits.
Authors: Blaazer AR; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands., Orrling KM; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands TI Pharma, Leiden, The Netherlands., Shanmugham A; IOTA Pharmaceuticals, Cambridge, UK., Jansen C; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands University of Dundee, Dundee, UK., Maes L; Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Belgium., Edink E; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands., Sterk GJ; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands., Siderius M; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands., England P; IOTA Pharmaceuticals, Cambridge, UK., Bailey D; IOTA Pharmaceuticals, Cambridge, UK., de Esch IJ; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands., Leurs R; Division of Medicinal Chemistry, Faculty of Sciences, Amsterdam Institute for Molecules, Medicines and Systems (AIMMS), VU University Amsterdam, Amsterdam, The Netherlands r.leurs@vu.nl.
Source: Journal of biomolecular screening [J Biomol Screen] 2015 Jan; Vol. 20 (1), pp. 131-40. Date of Electronic Publication: 2014 Sep 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 9612112 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-454X (Electronic) Linking ISSN: 10870571 NLM ISO Abbreviation: J Biomol Screen Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1552-454X
DOI:10.1177/1087057114549735